Hs00903280_cn

• Gene Symbol: CYP1A1
• Assay Reference Genome Location: Chr.15:74722356 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 1543
• Gene Name: cytochrome P450 family 1 subfamily A member 1
• Gene Aliases: AHH, AHRR, CP11, CYP1, CYPIA1, P1-450, P450-C, P450DX
• Location: Chr.15:74719542-74725610 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYP1A1	NM_000499.4	2	938	NP_000490.1
	NM_001319216.1	2	941	NP_001306145.1
	NM_001319217.1	2	941	NP_001306146.1
	XM_017021953.1			XP_016877442.1
	AK223108.1	2	859	BAD96828.1
	AK223113.1	2	856	BAD96833.1
	AK310810.1	2	985
	AK313880.1	2	856
	AM233517.1	2	230
	AM233518.1	2	230
	AM233519.1
	AM233520.1
	AM236046.1
	AM236047.1
	AY310359.1			AAQ76692.1
	AY871801.1	2	825
	BC023019.1	2	823	AAH23019.1
	K03191.1	2	828	AAA52139.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833055	Chr.15:74696003 - 74873947 on Build GRCh38	Loss	CYP1A1 SCAMP2 MIR4513 LMAN1L MIR6882 ULK3 CYP1A2 CPLX3 EDC3 CSK
esv3636907	Chr.15:74721538 - 74745196 on Build GRCh38	Loss	CYP1A1
nsv817698	Chr.15:74596822 - 74727108 on Build GRCh38	Gain	CYP1A1 ARID3B CLK3 LOC102723750 EDC3
esv2763106	Chr.15:74722123 - 74741845 on Build GRCh38	Loss	CYP1A1
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	UBL7-AS1 FAM219B UBL7 LOC732265 LOXL1-AS1 PML EDC3 CCDC33 ARID3B MIR6881 TBC1D21 COX5A LOC283731 NPTN CSK LOC107984728 STOML1 LMAN1L LOC105376731 MIR6882 C15orf39 C15orf59 HIGD2B RPP25 REC114 CYP1A1 ULK3 CD276 CYP1A2 LOC102723750 C15orf59-AS1 CPLX3 ISLR2 CYP11A1 SCAMP2 MIR4513 MPI SCAMP5 HCN4 LOXL1 ADPGK NEO1 GOLGA6A CLK3 LOC101929333 NPTN-IT1 BBS4 GOLGA6C SEMA7A PPCDC STRA6 ADPGK-AS1 LOC729739 ISLR

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to hypoxia
porphyrin-containing compound metabolic process
aging
cell proliferation
amine metabolic process
response to wounding
response to virus
response to nematode
response to herbicide
ethylene metabolic process
embryo development ending in birth or egg hatching
coumarin metabolic process
flavonoid metabolic process
response to iron(III) ion
insecticide metabolic process
drug metabolic process
dibenzo-p-dioxin catabolic process
epoxygenase P450 pathway
response to food
response to lipopolysaccharide
response to vitamin A
response to immobilization stress
vitamin D metabolic process
response to drug
9-cis-retinoic acid biosynthetic process
camera-type eye development
response to antibiotic
response to arsenic-containing substance
digestive tract development
hydrogen peroxide biosynthetic process
response to hyperoxia
oxidation-reduction process
maternal process involved in parturition
hepatocyte differentiation
demethylation
cellular response to organic cyclic compound
omega-hydroxylase P450 pathway
positive regulation of G1/S transition of mitotic cell cycle

Function(s)

monooxygenase activity
iron ion binding
protein binding
steroid hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on diphenols and related substances as donors
flavonoid 3'-monooxygenase activity
oxygen binding
enzyme binding
heme binding
demethylase activity
aromatase activity
vitamin D 24-hydroxylase activity