Hs00921639_cn

• Gene Symbol: FGD5
• Assay Reference Genome Location: Chr.3:14820017 on build GRCh38
• Cytoband: 3p25.1

Target Gene Details

• Entrez Gene ID: 152273
• Gene Name: FYVE, RhoGEF and PH domain containing 5
• Gene Aliases: ZFYVE23
• Location: Chr.3:14818962-14934565 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FGD5	NM_001320276.1	1	1056	NP_001307205.1
	NM_152536.3	1	1056	NP_689749.3
	XM_011533422.1	1	1056	XP_011531724.1
	XM_011533423.1	1	1056	XP_011531725.1
	AK131078.1	1	720	BAC85128.1
	BC132814.1	1	694
	BC132816.1	1	694
	BC144300.1	1	694
	BX640820.1			CAE45896.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2724945	Chr.3:13931758 - 14820330 on Build GRCh38	Deletion	CCDC174 TMEM43 GRIP2 C3orf20 XPC LINC01267 TPRXL FGD5 LSM3 LOC152274 CHCHD4 SLC6A6 FGD5P1
nsv589778	Chr.3:14765868 - 14823860 on Build GRCh38	Loss	LOC152274 C3orf20 FGD5
esv3893664	Chr.3:14808160 - 14845522 on Build GRCh38	Loss	LOC152274 FGD5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein modulator, protein-binding activity modulator, guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

cytoskeleton organization
regulation of cell shape
actin cytoskeleton organization
regulation of Rho protein signal transduction
regulation of GTPase activity
positive regulation of GTPase activity
filopodium assembly

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
small GTPase binding
metal ion binding