Hs00933380_cn

• Gene Symbol: GHRL
• Assay Reference Genome Location: Chr.3:10285769 on build GRCh38
• Cytoband: 3p25.3

Target Gene Details

• Entrez Gene ID: 51738
• Gene Name: ghrelin/obestatin prepropeptide
• Gene Aliases: MTLRP
• Location: Chr.3:10285750-10292947 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GHRL	NM_001134941.2			NP_001128413.1
	NM_001134944.1			NP_001128416.1
	NM_001134945.1			NP_001128417.1
	NM_001134946.1			NP_001128418.1
	NM_001302821.1			NP_001289750.1
	NM_001302822.1			NP_001289751.1
	NM_001302823.1			NP_001289752.1
	NM_001302824.1			NP_001289753.1
	NM_001302825.1			NP_001289754.1
	NM_016362.4			NP_057446.1
	NR_126505.1
	XM_017006612.1			XP_016862101.1
	XM_017006613.1			XP_016862102.1
	AB029434.1			BAA89371.1
	AB035700.1			BAB19045.1
	AJ252278.1			CAB65733.1
	AY184207.1			AAO27351.1
	AY359053.1			AAQ89412.1
	BC025791.1			AAH25791.1
	BM854032.1
	EF549557.1
	EF549569.1
	EF549571.1
	EF549572.1
	EF549573.1
	EF549574.1
	EF549575.1
	EU072083.1
	EU072084.1
	EU072085.1
	EU072086.1
	EU072087.1

Target Gene Details

• Entrez Gene ID: 100126793
• Gene Name: ghrelin opposite strand/antisense RNA
• Gene Aliases: GHRL-AS1, GHRLAS, NCRNA00068
• Location: Chr.3:10280952-10293449 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GHRLOS	NR_004431.3
	NR_024144.2
	NR_024145.2
	NR_073566.1
	NR_073567.1
	NR_073568.1
	EF549559.1
	EF549560.1
	EF549568.1
	EF549570.1
	EU072081.1
	EU072082.1
	EU789528.1
	EU789529.1
	EU789530.1
	EU789534.1
	EU789535.1
	EU789536.1
	EU789537.1
	EU789538.1
	EU789539.1
	EU789540.1
	EU789541.1
	EU789542.1
	EU789543.1
	EU789544.1
	EU789545.1
	EU789546.1
	EU789547.1
	EU789548.1
	EU789549.1
	EU789550.1
	EU789551.1
	EU789552.1

Target Gene Details

• Entrez Gene ID: 84657
• Gene Name: long intergenic non-protein coding RNA 852
• Gene Aliases: C3orf42, GHRL-AS2, GHRLOS2, NAG73
• Location: Chr.3:10284419-10285746 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LINC00852	NR_026829.1
	AF085991.1
	AF280797.2			AAK15459.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv436362	Chr.3:10048344 - 11860564 on Build GRCh38	Deletion	VGLL4 HRH1 TATDN2 ATP2B2 MIR885 ATP2B2-IT2 BRK1 SLC6A1 MIR378B TAMM41 SEC13 FANCD2 LINC00606 ATG7 SLC6A1-AS1 FANCD2OS GHRL SLC6A11 LOC101927467 GHRLOS VHL IRAK2 LINC00852
nsv508903	Chr.3:10275353 - 10401894 on Build GRCh38	Insertion	SEC13 TATDN2 ATP2B2 MIR885 GHRL MIR378B GHRLOS LINC00852
nsv589650	Chr.3:10260488 - 10294102 on Build GRCh38	Loss	TATDN2 GHRL GHRLOS LINC00852
dgv762e201	Chr.3:10008967 - 11913136 on Build GRCh38	Deletion	TATDN2 MIR885 ATP2B2-IT2 MIR378B EMC3 SEC13 FANCD2 ATG7 GHRL IRAK2 VGLL4 HRH1 ATP2B2 BRK1 SLC6A1 TAMM41 LOC401052 LINC00606 SLC6A1-AS1 FANCD2OS SLC6A11 FANCD2P2 LOC101927467 GHRLOS VHL LINC00852 CIDECP
nsv1121603	Chr.3:10071433 - 11889279 on Build GRCh38	Deletion	VGLL4 HRH1 TATDN2 ATP2B2 MIR885 ATP2B2-IT2 BRK1 SLC6A1 MIR378B TAMM41 SEC13 FANCD2 LINC00606 ATG7 SLC6A1-AS1 FANCD2OS GHRL SLC6A11 FANCD2P2 LOC101927467 GHRLOS VHL IRAK2 LINC00852
nsv436869	Chr.3:10064456 - 11877985 on Build GRCh38	Insertion	VGLL4 HRH1 TATDN2 ATP2B2 MIR885 ATP2B2-IT2 BRK1 SLC6A1 MIR378B TAMM41 SEC13 FANCD2 LINC00606 ATG7 SLC6A1-AS1 FANCD2OS GHRL SLC6A11 FANCD2P2 LOC101927467 GHRLOS VHL IRAK2 LINC00852
nsv1073204	Chr.3:9996548 - 11875005 on Build GRCh38	Deletion	TATDN2 MIR885 ATP2B2-IT2 MIR378B EMC3 SEC13 FANCD2 ATG7 GHRL EMC3-AS1 IRAK2 VGLL4 HRH1 ATP2B2 BRK1 SLC6A1 TAMM41 LOC401052 LINC00606 SLC6A1-AS1 FANCD2OS SLC6A11 FANCD2P2 LOC101927467 GHRLOS VHL LINC00852 CIDECP

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

peptide hormone

Gene Ontology Categories:

Process(es)

activation of MAPK activity
gastric acid secretion
negative regulation of endothelial cell proliferation
glucose metabolic process
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
actin polymerization or depolymerization
adult feeding behavior
response to hormone
hormone-mediated signaling pathway
dendrite development
negative regulation of angiogenesis
growth hormone secretion
positive regulation of insulin secretion
regulation of response to food
positive regulation of appetite
negative regulation of interleukin-1 beta production
negative regulation of locomotion
positive regulation of multicellular organism growth
regulation of cell proliferation
negative regulation of circadian sleep/wake cycle, REM sleep
negative regulation of tumor necrosis factor biosynthetic process
negative regulation of apoptotic process
cortisol secretion
response to estrogen
negative regulation of interleukin-6 biosynthetic process
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of insulin secretion
decidualization
negative regulation of inflammatory response
cartilage development
positive regulation of corticotropin secretion
positive regulation of cortisol secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
positive regulation of growth hormone secretion
positive regulation of growth hormone receptor signaling pathway
positive regulation of protein tyrosine kinase activity
negative regulation of energy homeostasis
positive regulation of energy homeostasis

Function(s)

G-protein coupled receptor binding
protein binding
growth hormone-releasing hormone activity
protein tyrosine kinase activator activity
ghrelin receptor binding