Hs00948610_cn

• Gene Symbol: ISLR2
• Assay Reference Genome Location: Chr.15:74135176 on build GRCh38
• Cytoband: 15q24.1

Target Gene Details

• Entrez Gene ID: 57611
• Gene Name: immunoglobulin superfamily containing leucine rich repeat 2
• Gene Aliases: LINX
• Location: Chr.15:74128203-74141826 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ISLR2	NM_001130136.1	4	3191	NP_001123608.1
	NM_001130137.1	4	2927	NP_001123609.1
	NM_001130138.1	4	2635	NP_001123610.1
	NM_020851.2	3	2760	NP_065902.1
	XM_011521840.2	4	3030	XP_011520142.1
	XM_011521841.1	4	2713	XP_011520143.1
	XM_017022446.1			XP_016877935.1
	AB040898.2	4	3191
	AK092297.1	3	2586
	AK092302.1	4	3207
	AK096602.1	2	2538
	AK290467.1
	AY358316.1	3	2558	AAQ88682.1
	BC114551.1	3	1274	AAI14552.1
	BC152429.1	4	3191

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833053	Chr.15:74067815 - 74262799 on Build GRCh38	Loss	CCDC33 ISLR2 ISLR LOC732265 GOLGA6A STRA6 LOC283731
nsv1050884	Chr.15:74102642 - 74197072 on Build GRCh38	Gain	ISLR2 ISLR STRA6 LOC283731
nsv469619	Chr.15:73999518 - 74173980 on Build GRCh38	Loss	ISLR2 ISLR LOC732265 GOLGA6A PML LOC283731
nsv827385	Chr.15:74127198 - 74136960 on Build GRCh38	Gain	ISLR2 LOC283731
nsv951993	Chr.15:74124460 - 74137359 on Build GRCh38	Deletion	ISLR2 LOC283731
esv2760040	Chr.15:73922773 - 74172575 on Build GRCh38	Gain+Loss	ISLR2 LOC732265 STOML1 GOLGA6A LOXL1-AS1 LOXL1 PML LOC283731
nsv1047564	Chr.15:74116495 - 74165840 on Build GRCh38	Gain	ISLR2 LOC283731
nsv1121512	Chr.15:72670085 - 75273877 on Build GRCh38	Deletion	CCDC33 RPP25 LOC105376731 TBC1D21 REC114 STOML1 LOC107984728 C15orf59 COX5A MIR6881 NPTN LOC283731 ADPGK ISLR LOC732265 UBL7 NPTN-IT1 C15orf59-AS1 NEO1 HIGD2B GOLGA6A CYP11A1 CD276 CYP1A1 LOC729739 CPLX3 ARID3B STRA6 HCN4 MPI ULK3 LOXL1-AS1 CSK PML UBL7-AS1 SCAMP2 ADPGK-AS1 LMAN1L CLK3 SEMA7A EDC3 C15orf39 LOC101929333 MIR4513 PPCDC ISLR2 LOC102723750 FAM219B GOLGA6C SCAMP5 LOXL1 BBS4 MIR6882 CYP1A2

More Information

Additional Information:

For this assay, SNP(s) [rs114366458] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

immunoglobulin superfamily cell adhesion molecule

Gene Ontology Categories:

Process(es)

positive regulation of axon extension