Hs01078960_cn

• Gene Symbol: MED12L
• Assay Reference Genome Location: Chr.3:151328245 on build GRCh38
• Cytoband: 3q25.1

Target Gene Details

• Entrez Gene ID: 116931
• Gene Name: mediator complex subunit 12 like
• Gene Aliases: NOPAR, TNRC11L, TRALP, TRALPUSH
• Location: Chr.3:151085665-151436677 on Build GRCh38
• Assay Gene Location: Within Intron 16

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MED12L	NM_053002.5			NP_443728.3
	XM_006713487.3			XP_006713550.1
	XM_011512390.2			XP_011510692.1
	XM_011512394.2			XP_011510696.1
	XM_011512399.2			XP_011510701.1
	XM_017005676.1			XP_016861165.1
	XM_017005677.1			XP_016861166.1
	XM_017005678.1			XP_016861167.1
	XM_017005679.1			XP_016861168.1
	XM_017005680.1			XP_016861169.1
	AB046855.1			BAB13461.1
	AF399708.1			AAO38813.1
	AK128165.1
	BC144559.1
	BX108326.1

Target Gene Details

• Entrez Gene ID: 53829
• Gene Name: purinergic receptor P2Y13
• Gene Aliases: FKSG77, GPCR1, GPR86, GPR94, P2Y13, SP174
• Location: Chr.3:151326308-151329549 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
P2RY13	NM_176894.2	2	832	NP_795713.2
	XM_006713664.1			XP_006713727.1
	AF178982.1	1	303	AAK18752.1
	AF295368.1	1	921	AAK01864.1
	AF345565.1	1	781	AAK29068.1
	AF406692.1	1	748	AAL01038.1
	AK313208.1	2	831
	BC041116.1	2	805	AAH41116.2
	BC066887.1	1	747	AAH66887.1
	JF810883.1	2	811

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829757	Chr.3:151327092 - 151508654 on Build GRCh38	Loss	IGSF10 MED12L P2RY12 P2RY13
nsv954492	Chr.3:151315313 - 151363512 on Build GRCh38	Duplication	MED12L P2RY12 GPR87 P2RY13
nsv592045	Chr.3:151052827 - 151377305 on Build GRCh38	Gain	MED12L P2RY12 P2RY14 CLRN1-AS1 GPR87 GPR171 P2RY13

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor, G-protein coupled receptor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of adenylate cyclase activity
biological_process
G-protein coupled purinergic nucleotide receptor signaling pathway
cellular response to organic cyclic compound

Function(s)

RNA polymerase II transcription coactivator activity
beta-catenin binding
G-protein coupled purinergic nucleotide receptor activity