Hs01251979_cn

• Gene Symbol: PLA2G2D
• Assay Reference Genome Location: Chr.1:20114241 on build GRCh38
• Cytoband: 1p36.12

Target Gene Details

• Entrez Gene ID: 26279
• Gene Name: phospholipase A2 group IID
• Gene Aliases: PLA2IID, SPLASH, sPLA2-IID, sPLA2S
• Location: Chr.1:20112650-20119566 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLA2G2D	NM_001271814.1			NP_001258743.1
	NM_012400.3			NP_036532.1
	AF112982.1			AAD51390.1
	AF188625.1			AAF09020.1
	AK290406.1
	AK301396.1
	AK310156.1
	AK311903.1
	BC025706.1			AAH25706.1
	DC295429.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv1003821	Chr.1:20104576 - 20116485 on Build GRCh38	Deletion	PLA2G2D
nsv545731	Chr.1:19989106 - 20776306 on Build GRCh38	Gain	PLA2G2F UBXN10 CAMK2N1 HP1BP3 PLA2G2D FAM43B PLA2G5 PINK1 PINK1-AS VWA5B1 DDOST UBXN10-AS1 PLA2G2C LINC01141 KIF17 MIR6084 MUL1 SH2D5 CDA
nsv1003802	Chr.1:20057935 - 20154347 on Build GRCh38	Loss	PLA2G2F PLA2G2D PLA2G5
nsv5520	Chr.1:20071053 - 20115978 on Build GRCh38	Deletion	PLA2G2D PLA2G5

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phospholipase

Gene Ontology Categories:

Process(es)

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
phospholipid metabolic process
phosphatidic acid biosynthetic process
inflammatory response
lipid catabolic process
phosphatidylglycerol acyl-chain remodeling
phosphatidylinositol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
negative regulation of T cell proliferation

Function(s)

phospholipase A2 activity
calcium ion binding
heparin binding
heparan sulfate proteoglycan binding