Hs01262259_cn

• Gene Symbol: TOP3A
• Assay Reference Genome Location: Chr.17:18274464 on build GRCh38
• Cytoband: 17p11.2

Target Gene Details

• Entrez Gene ID: 7156
• Gene Name: topoisomerase (DNA) III alpha
• Gene Aliases: TOP3, ZGRF7
• Location: Chr.17:18269958-18315092 on Build GRCh38
• Assay Gene Location: Within Exon 19

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TOP3A	NM_001320759.1	18	3584	NP_001307688.1
	NM_004618.4	19	3658	NP_004609.1
	XM_011524001.2	14	2749	XP_011522303.1
	AF086042.1
	AK126869.1	13	2699
	AK290513.1	8	1969
	AK292926.1	19	3481
	BC051748.1	19	3540	AAH51748.1
	BY996313.1	1	335
	U43431.1	19	3521	AAB03694.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv833386	Chr.17:18266947 - 18429412 on Build GRCh38	Gain	SHMT1 KRT17P5 KRT17P2 EVPLL SMCR8 MIR6778 TOP3A FLJ35934

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA synthesis involved in DNA repair
strand displacement
DNA replication
DNA topological change
meiotic nuclear division
regulation of signal transduction by p53 class mediator

Function(s)

DNA binding
DNA topoisomerase activity
DNA topoisomerase type I activity
protein binding
zinc ion binding