Hs01283252_cn

• Gene Symbol: POLN
• Assay Reference Genome Location: Chr.4:2075478 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 353497
• Gene Name: DNA polymerase nu
• Gene Aliases: POL4P
• Location: Chr.4:2071958-2242164 on Build GRCh38
• Assay Gene Location: Overlaps Intron 24 - Exon 24

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLN	NM_181808.3			NP_861524.2
	AF044578.1			AAD02338.1
	AL122048.1
	AY136549.1			AAN52116.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2726835	Chr.4:2019561 - 2959568 on Build GRCh38	Deletion	NOP14-AS1 NAT8L C4orf48 MXD4 ADD1 CFAP99 NOP14 SH3BP2 MFSD10 HAUS3 RNF4 MIR4800 TNIP2 FAM193A POLN ZFYVE28
dgv8909n54	Chr.4:2058874 - 2075739 on Build GRCh38	Loss	NAT8L POLN
nsv949757	Chr.4:2056974 - 2082173 on Build GRCh38	Deletion	NAT8L POLN
nsv822441	Chr.4:1991240 - 2080440 on Build GRCh38	Loss	NELFA NAT8L C4orf48 POLN

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed DNA polymerase

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
DNA-dependent DNA replication
translesion synthesis
interstrand cross-link repair
nucleic acid phosphodiester bond hydrolysis

Function(s)

DNA binding
DNA-directed DNA polymerase activity
protein binding
5'-3' exonuclease activity
cyclin binding