Hs01294458_cn

• Gene Symbol: SLF2
• Assay Reference Genome Location: Chr.10:100924271 on build GRCh38
• Cytoband: 10q24.31

Target Gene Details

• Entrez Gene ID: 55719
• Gene Name: SMC5-SMC6 complex localization factor 2
• Gene Aliases: C10orf6, FAM178A
• Location: Chr.10:100910230-100965134 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLF2	NM_001136123.1	5	1812	NP_001129595.1
	NM_018121.3	5	1812	NP_060591.3
	XM_005269965.2	5	1427	XP_005270022.1
	XM_011539944.2	5	4402	XP_011538246.1
	AF460991.1	5	1812	AAN84475.1
	AK057741.1	3	377	BAB71557.1
	AK292565.1	5	1429
	AL832343.1	5	1418
	AL832383.1	5	1380
	AL833126.1	5	1419

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831965	Chr.10:100916724 - 101082796 on Build GRCh38	Loss	PDZD7 MIR608 MRPL43 KAZALD1 SEMA4G SLF2 SFXN3 C10orf2 LZTS2
nsv552051	Chr.10:100904892 - 100984619 on Build GRCh38	Loss	MIR608 MRPL43 SEMA4G SLF2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

DNA repair
cellular response to DNA damage stimulus
positive regulation of protein complex assembly
positive regulation of maintenance of mitotic sister chromatid cohesion
protein localization to site of double-strand break
positive regulation of double-strand break repair

Function(s)

protein binding
ubiquitin protein ligase binding
protein complex binding