Hs01306743_cn

• Gene Symbol: FBXW5
• Assay Reference Genome Location: Chr.9:136943948 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54461
• Gene Name: F-box and WD repeat domain containing 5
• Gene Aliases: Fbw5
• Location: Chr.9:136940433-136944774 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FBXW5	NM_018998.3	2	320	NP_061871.1
	XM_005266089.2	2	340	XP_005266146.2
	XM_011518789.1	2	340	XP_011517091.1
	XM_017014812.1	2	340	XP_016870301.1
	AK026081.1	2	184	BAB15354.1
	AK315738.1	2	195
	BC014130.1	2	216	AAH14130.1
	BC014297.2	2	187	AAH14297.1
	BI829307.1	2	287
	CF132404.1	2	261
	DB460097.1	2	304

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951205	Chr.9:136821949 - 136944648 on Build GRCh38	Deletion	MIR4479 FBXW5 C9orf172 PHPT1 EDF1 RABL6 MIR4292 MAMDC4 TRAF2
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	LCN15 PTGDS C8G C9orf142 LCN10 C9orf172 TMEM141 CCDC183 LCN12 LOC100128593 PHPT1 LCN6 TRAF2 CCDC183-AS1 FBXW5 ABCA2 CLIC3 MIR6722 MIR4479 LCNL1 EDF1 RABL6 MIR4292 PRR31 MAMDC4 LCN8
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	PTGDS C8G C9orf142 C9orf172 DPP7 MIR7114 LCN12 PNPLA7 SAPCD2 NPDC1 NSMF PHPT1 TPRN ANAPC2 EXD3 UAP1L1 TUBB4B CLIC3 MIR3621 NDOR1 MIR4479 MAN1B1-AS1 STPG3 LCNL1 NELFB PRR31 TOR4A RNF208 MAN1B1 SLC34A3 ENTPD2 GRIN1 ENTPD8 NOXA1 TMEM203 CCDC183 FUT7 C9orf173-AS1 NRARP LRRC26 TMEM210 TRAF2 CCDC183-AS1 FBXW5 SSNA1 ABCA2 FAM166A CYSRT1 C9orf139 EDF1 LOC101930307 RABL6 MIR4292 MAMDC4 RNF224
nsv615987	Chr.9:136939743 - 136947810 on Build GRCh38	Loss	FBXW5 C8G
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	SDCCAG3 PTGDS SEC16A C8G C9orf142 LCN10 C9orf172 DPP7 SNORA17B MIR4673 TMEM141 DNLZ FAM69B LCN12 SAPCD2 SNAPC4 NPDC1 PHPT1 NALT1 LCN6 SNHG7 UAP1L1 CARD9 LINC01451 CLIC3 MIR6722 MIR3621 MIR4479 MAN1B1-AS1 INPP5E LCNL1 MIR126 PRR31 LCN15 MAN1B1 ENTPD2 GRIN1 CCDC183 FUT7 LOC100128593 PMPCA HSPC324 LRRC26 MIR4674 TMEM210 TRAF2 CCDC183-AS1 FBXW5 ABCA2 EGFL7 SNORA17A C9orf163 NOTCH1 AGPAT2 C9orf139 EDF1 LOC101930307 RABL6 MIR4292 MAMDC4 LCN8
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	PTGDS C8G C9orf142 LCN10 C9orf172 DPP7 SNORA17B TMEM141 FAM69B LCN12 SAPCD2 NPDC1 PHPT1 LCN6 SNHG7 TPRN ANAPC2 EXD3 UAP1L1 TUBB4B LINC01451 CLIC3 MIR6722 MIR3621 NDOR1 MIR4479 MAN1B1-AS1 STPG3 LCNL1 MIR126 NELFB PRR31 LCN15 TOR4A RNF208 MAN1B1 SLC34A3 ENTPD2 GRIN1 TMEM203 CCDC183 FUT7 LOC100128593 C9orf173-AS1 HSPC324 NRARP LRRC26 TMEM210 TRAF2 CCDC183-AS1 FBXW5 SSNA1 ABCA2 FAM166A EGFL7 SNORA17A CYSRT1 AGPAT2 C9orf139 EDF1 LOC101930307 RABL6 MIR4292 MAMDC4 RNF224 LCN8
nsv482133	Chr.9:136940436 - 136944721 on Build GRCh38	Gain	FBXW5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
regulation of centrosome duplication
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process

Function(s)

protein binding
protein kinase binding