Hs01350091_cn

• Gene Symbol: POLR2B
• Assay Reference Genome Location: Chr.4:56994441 on build GRCh38
• Cytoband: 4q12

Target Gene Details

• Entrez Gene ID: 5431
• Gene Name: RNA polymerase II subunit B
• Gene Aliases: POL2RB, RPB2, hRPB140
• Location: Chr.4:56978640-57031162 on Build GRCh38
• Assay Gene Location: Overlaps Intron 4 - Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR2B	NM_000938.2			NP_000929.1
	NM_001303268.1			NP_001290197.1
	NM_001303269.1			NP_001290198.1
	AK289823.1
	AK294901.1
	AK295132.1
	AK299090.1
	BC023503.2			AAH23503.2
	X63563.1			CAA45124.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5214n100	Chr.4:56786612 - 56999637 on Build GRCh38	Gain	SPINK2 REST POLR2B NOA1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

RNA polymerase II activity
DNA binding
chromatin binding
protein binding
ribonucleoside binding
poly(A) RNA binding
metal ion binding