Hs01351626_cn

• Gene Symbol: LRRC4
• Assay Reference Genome Location: Chr.7:128029542 on build GRCh38
• Cytoband: 7q32.1

Target Gene Details

• Entrez Gene ID: 64101
• Gene Name: leucine rich repeat containing 4
• Gene Aliases: NAG14, NGL-2
• Location: Chr.7:128027071-128032273 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LRRC4	NM_022143.4	2	1236	NP_071426.1
	XM_011516461.2	3	1542	XP_011514763.1
	XM_017012505.1	3	1432	XP_016867994.1
	AF196976.4	2	1239	AAG28019.2
	AJ297858.1	2	1239	CAC82651.1
	AK172751.1	2	1240	BAD18737.1
	AK314047.1	2	1312
	AY358307.1	1	1155	AAQ88674.1
	BC111561.1	2	1230
	BC111745.1	2	1230

Target Gene Details

• Entrez Gene ID: 27044
• Gene Name: staphylococcal nuclease and tudor domain containing 1
• Gene Aliases: TDRD11, p100
• Location: Chr.7:127652119-128092607 on Build GRCh38
• Assay Gene Location: Within Intron 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SND1	NM_014390.2			NP_055205.2
	AB209510.1			BAD92747.1
	AK096583.1
	AK304181.1
	AK309014.1
	AK312313.1
	BC017180.2
	BE799345.1
	BT009785.1			AAP88787.1
	U22055.1			AAA80488.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv5944	Chr.7:128024907 - 128058792 on Build GRCh38	Insertion	SND1 LRRC4
nsv1024743	Chr.7:127858642 - 128029951 on Build GRCh38	Gain	SND1 SND1-IT1 LRRC4

More Information

Additional Information:

For this assay, SNP(s) [rs73238074] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

negative regulation of protein kinase activity
cytokine-mediated signaling pathway
negative regulation of JAK-STAT cascade
regulation of synapse organization
postsynaptic density protein 95 clustering
osteoblast differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
viral process
gene silencing by RNA
nucleic acid phosphodiester bond hydrolysis
cell-cell adhesion

Function(s)

protein kinase inhibitor activity
protein binding
transcription cofactor activity
nuclease activity
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion