Hs01355691_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143993213 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1	7	1766	NP_000828.1
	NM_001009184.1	7	1654	NP_001009184.1
	AB097026.1	7	1578	BAC77379.1
	AK127640.1	7	1802
	AL157442.1	1	497	CAB75662.3
	BC041788.1	7	1612	AAH41788.2
	BC084553.1	6	1503	AAH84553.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PLEC PARP10 GRINA
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	MIR1234 WDR97 RECQL4 GRINA GPT LOC101928953 MIR6847 SLC39A4 SHARPIN LRRC14 HSF1 FBXL6 LOC101928902 MIR6848 MROH1 BOP1 SCX TMEM249 MIR6849 CPSF1 MFSD3 PPP1R16A KIFC2 VPS28 PLEC SLC52A2 ADCK5 SCRT1 MAF1 EXOSC4 CYHR1 TONSL-AS1 FOXH1 SMPD5 TONSL MIR939 SPATC1 MIR7112 DGAT1 MIR6846 OPLAH GPAA1 PARP10 MIR6893 HGH1 MIR661 CYC1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	MIR1234 WDR97 RECQL4 GRINA GPT LOC101928953 MIR6847 SLC39A4 SHARPIN LRRC14 HSF1 FBXL6 LOC101928902 MIR6848 MROH1 BOP1 SCX TMEM249 MIR6849 CPSF1 MFSD3 PPP1R16A KIFC2 VPS28 PLEC SLC52A2 ADCK5 SCRT1 MAF1 EXOSC4 CYHR1 TONSL-AS1 FOXH1 SMPD5 TONSL MIR939 SPATC1 MIR7112 DGAT1 MIR6846 OPLAH GPAA1 PARP10 MIR6893 HGH1 MIR661 CYC1
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	PLEC WDR97 GRINA MAF1 EXOSC4 MIR6847 SMPD5 SHARPIN SPATC1 MIR6846 OPLAH GPAA1 PARP10 CYC1
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	PLEC WDR97 GRINA MAF1 EXOSC4 MIR6847 SMPD5 SHARPIN SPATC1 EPPK1 MIR6846 OPLAH GPAA1 PARP10 HGH1 MROH1 MIR661 CYC1
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	PLEC WDR97 GRINA MAF1 EXOSC4 MIR6847 SMPD5 SHARPIN SPATC1 EPPK1 MIR6846 OPLAH GPAA1 PARP10 MIR661 CYC1
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	PLEC MIR6845 NRBP2 GRINA EXOSC4 MIR6847 LOC642574 SCRIB SMPD5 SPATC1 EPPK1 MIR6846 OPLAH PARP10 PUF60 MIR661 MIR937
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	PLEC MIR6846 OPLAH GPAA1 PARP10 GRINA EXOSC4 MIR6847 SMPD5 MIR661 SPATC1 CYC1
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	PLEC WDR97 GRINA MAF1 EXOSC4 MIR6847 SMPD5 SHARPIN SPATC1 MIR6846 OPLAH GPAA1 PARP10 MIR661 CYC1
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	PLEC MIR6846 OPLAH GPAA1 PARP10 GRINA EXOSC4 MIR6847 SMPD5 MIR661 SPATC1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding