Hs01356784_cn

• Gene Symbol: NDRG2
• Assay Reference Genome Location: Chr.14:21034173 on build GRCh38
• Cytoband: 14q11.2

Target Gene Details

• Entrez Gene ID: 57447
• Gene Name: NDRG family member 2
• Gene Aliases: SYLD
• Location: Chr.14:21016763-21070872 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NDRG2	NM_001282211.1			NP_001269140.1
	AK293514.1

Target Gene Details

• Entrez Gene ID: 440163
• Gene Name: ribonuclease A family member 13 (inactive)
• Gene Aliases: HEL-S-86p, RAL1
• Location: Chr.14:21032820-21034785 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RNASE13	NM_001012264.3	2	254	NP_001012264.1
	AY665808.1	1	116	AAV87186.1
	BC044831.1	2	254	AAH44831.1
	FJ237363.1	2	254

Target Gene Details

• Entrez Gene ID: 122664
• Gene Name: tubulin polymerization promoting protein family member 2
• Gene Aliases: C14orf8, CT152, P18, p25beta
• Location: Chr.14:21024262-21036352 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TPPP2	XM_011536416.1			XP_011534718.1
	XM_011536420.2			XP_011534722.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428293	Chr.14:20747949 - 21063624 on Build GRCh38	Gain+Loss	EDDM3A RNASE13 ARHGEF40 TPPP2 METTL17 SLC39A2 RNASE6 LOC101929718 NDRG2 RNASE7 RNASE1 MIR6717 RNASE2 EDDM3B RNASE8 RNASE3 ECRP
nsv832740	Chr.14:20863901 - 21076893 on Build GRCh38	Gain	RNASE13 ARHGEF40 TPPP2 METTL17 SLC39A2 LOC101929718 NDRG2 RNASE7 MIR6717 RNASE2 RNASE8 RNASE3 ECRP
nsv1039369	Chr.14:21030895 - 21062142 on Build GRCh38	Loss	RNASE13 ARHGEF40 RNASE8 TPPP2 NDRG2 RNASE7

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease, non-motor microtubule binding protein

Gene Ontology Categories:

Process(es)

negative regulation of cytokine production
signal transduction
regulation of vascular endothelial growth factor production
Wnt signaling pathway
substantia nigra development
cell differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of ERK1 and ERK2 cascade
regulation of platelet-derived growth factor production

Function(s)

molecular_function
protein binding
nucleic acid binding
endonuclease activity
ribonuclease activity