Hs01371653_cn

• Gene Symbol: LOC115110
• Assay Reference Genome Location: Chr.1:2556614 on build GRCh38
• Cytoband: 1p36.32

Target Gene Details

• Entrez Gene ID: 115110
• Gene Name: uncharacterized LOC115110
• Gene Aliases: -
• Location: Chr.1:2549920-2557011 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC115110	NR_037844.2	2	118
	AK128532.1	2	118	BAC87484.1

Target Gene Details

• Entrez Gene ID: 8764
• Gene Name: TNF receptor superfamily member 14
• Gene Aliases: ATAR, CD270, HVEA, HVEM, LIGHTR, TR2
• Location: Chr.1:2555767-2565622 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF14	NM_001297605.1	1	250	NP_001284534.1
	NM_003820.3	1	250	NP_003811.2
	XM_006711019.2			XP_006711082.1
	XM_017002720.1			XP_016858209.1
	XM_017002721.1			XP_016858210.1
	AB208808.1			BAD92045.1
	AF153978.1	1	195	AAF75588.1
	AK300515.1	1	250
	AK303468.1	1	244
	AK310076.1
	AY358879.1			AAQ89238.1
	BC002794.2	1	216	AAH02794.1
	BC029848.1			AAH29848.1
	BX343044.2
	DC383433.1	1	250
	U70321.1	1	249	AAB58354.1
	U81232.1	1	214	AAD00505.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv951557	Chr.1:2266062 - 2564661 on Build GRCh38	Deletion	LOC100129534 LOC115110 PEX10 MORN1 PLCH2 PANK4 RER1 TNFRSF14 HES5 SKI
nsv545077	Chr.1:2428542 - 2622185 on Build GRCh38	Gain	FAM213B LOC115110 MMEL1 LOC100996583 PLCH2 PANK4 TNFRSF14 HES5
nsv545082	Chr.1:2536231 - 2597243 on Build GRCh38	Loss	FAM213B LOC115110 MMEL1 LOC100996583 TNFRSF14
nsv470684	Chr.1:2394570 - 2930923 on Build GRCh38	Loss	FAM213B LOC115110 TTC34 MMEL1 LOC100996583 PEX10 PLCH2 PANK4 RER1 TNFRSF14 HES5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of cytokine secretion involved in immune response
inflammatory response
immune response
cell surface receptor signaling pathway
multicellular organism development
T cell costimulation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of alpha-beta T cell proliferation
viral entry into host cell
positive regulation of peptidyl-tyrosine phosphorylation
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
apoptotic signaling pathway
positive regulation of T cell migration

Function(s)

virus receptor activity
tumor necrosis factor-activated receptor activity
protein binding
ubiquitin protein ligase binding