Hs01399566_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37126444 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3	10	3439	NP_000869.1
	BC025691.1	10	3422	AAH25691.1
	M26062.1	10	3439	AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	LOC102724378 LOC101927051 LOC100506271 TRIOBP NOL12 MFNG ELFN2 SH3BP1 MPST TST KCTD17 RAC2 IL2RB LGALS1 TEX33 C1QTNF6 SSTR3 CARD10 CYTH4 TMPRSS6 LGALS2 GGA1 PDXP CDC42EP1
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	TEX33 LL22NC01-81G9.3 TMPRSS6 MPST TST KCTD17 IL2RB
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	TEX33 LL22NC01-81G9.3 C1QTNF6 TMPRSS6 MPST TST KCTD17 IL2RB
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	TEX33 LL22NC01-81G9.3 TMPRSS6 MPST TST KCTD17 IL2RB

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding