Hs01400741_cn

• Gene Symbol: POLR3D
• Assay Reference Genome Location: Chr.8:22247267 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 661
• Gene Name: RNA polymerase III subunit D
• Gene Aliases: BN51T, RPC4, RPC53, TSBN51
• Location: Chr.8:22245104-22251167 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3D	NM_001722.2			NP_001713.2
	AK026588.1
	AK295725.1
	AY092086.1			AAM18216.1
	BC002603.2			AAH02603.1
	BC004484.2			AAH04484.1
	CR536509.1			CAG38747.1
	CR541803.1			CAG46602.1
	M17754.1			AAA51838.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470205	Chr.8:22191277 - 22256052 on Build GRCh38	Loss	LOC100507071 MIR320A PHYHIP POLR3D BMP1
dgv12054n54	Chr.8:22045805 - 22251098 on Build GRCh38	Loss	DMTN LGI3 REEP4 MIR320A FGF17 PHYHIP NUDT18 FAM160B2 POLR3D BMP1 HR SFTPC
nsv831265	Chr.8:22199688 - 22366918 on Build GRCh38	Loss	LOC100507071 MIR320A PIWIL2 PHYHIP POLR3D BMP1
nsv831264	Chr.8:22093700 - 22328040 on Build GRCh38	Gain+Loss	LGI3 REEP4 LOC100507071 MIR320A PIWIL2 PHYHIP NUDT18 FAM160B2 POLR3D BMP1 HR SFTPC
esv2759604	Chr.8:20675533 - 23254096 on Build GRCh38	Loss	REEP4 PEBP4 MIR320A LOC254896 LOC107984124 TNFRSF10C BMP1 BIN3-IT1 HR DOK2 DMTN LOC102467222 RHOBTB2 LOC101929172 LOC100507071 EGR3 C8orf58 LOC286114 NUDT18 FAM160B2 LOC101929237 LOC286059 TNFRSF10A LGI3 BIN3 TNFRSF10B NPM2 FGF17 TNFRSF10D GFRA2 PHYHIP SLC39A14 XPO7 SORBS3 PPP3CC LOC389641 PIWIL2 LOC107986876 POLR3D CHMP7 CCAR2 PDLIM2 SFTPC

More Information

Additional Information:

For this assay, SNP(s) [rs145048190] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of interferon-beta production
innate immune response
positive regulation of innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
DNA binding
chromatin binding