Hs01404754_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82831811 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	2	955	NP_078978.2
	AK023903.1	2	924	BAB14718.1
	AK301690.1
	BC109036.1	2	914	AAI09037.1
	BC109037.1	2	914	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	WDR45B TBCD B3GNTL1 MIR4525 LOC105376791 FN3KRP FOXK2 FN3K METRNL ZNF750 LOC105371944 LOC101929552 RAB40B
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	FN3K ZNF750 TBCD LOC101929552 MIR4525 LOC105376791 FN3KRP RAB40B
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	NPLOC4 NARF HGS CD7 MRPL12 LOC101929511 OGFOD3 ANAPC11 STRA13 GPS1 FN3KRP PYCR1 FN3K ACTG1 UTS2R LOC105371944 LOC105371925 TSPAN10 CSNK1D CCDC57 DCXR GCGR AATK-AS1 C17orf89 SIRT7 SLC38A10 HEXDC C17orf62 SECTM1 B3GNTL1 OXLD1 PPP1R27 P4HB CCDC137 MIR4525 ALYREF ASPSCR1 MIR6787 TEX19 TEPSIN ARL16 ARHGDIA MIR6786 MAFG-AS1 LINC00482 BAHCC1 RAB40B LOC105376790 FAAP100 DUS1L SNORD134 MCRIP1 AATK WDR45B MIR3186 NPB FOXK2 CEP131 ZNF750 RAC3 TMEM105 SLC25A10 MYADML2 RFNG FSCN2 TBCD FASN SLC16A3 LOC105376791 NOTUM PCYT2 MIR4740 LRRC45 MAFG PDE6G LOC101929552 LOC100130370
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	ZNF750 TBCD
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	ZNF750 TBCD
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	LOC105376790 NARF WDR45B HEXDC TBCD C17orf62 SECTM1 CD7 LOC101929511 OGFOD3 MIR4525 LOC105376791 FN3KRP FOXK2 TEX19 FN3K ZNF750 UTS2R CSNK1D LOC101929552 RAB40B
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	NARF CD7 LOC101929511 OGFOD3 ANAPC11 STRA13 GPS1 FN3KRP PYCR1 FN3K UTS2R LOC105371944 CSNK1D CCDC57 DCXR SIRT7 HEXDC C17orf62 SECTM1 B3GNTL1 PPP1R27 P4HB MIR4525 ALYREF ASPSCR1 MIR6787 TEX19 ARHGDIA MAFG-AS1 RAB40B LOC105376790 DUS1L SNORD134 MCRIP1 WDR45B NPB FOXK2 METRNL ZNF750 RAC3 MYADML2 RFNG TBCD FASN SLC16A3 LOC105376791 NOTUM PCYT2 LRRC45 MAFG LOC101929552

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding