Hs01422812_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136977663 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AK075333.1
	AK312817.1
	AY026356.1			AAK07679.1
	BC005939.1			AAH05939.1
	BG037037.1
	BM686612.1
	BT019921.1			AAV38724.1
	BT019922.1			AAV38725.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv615997	Chr.9:136977199 - 136984376 on Build GRCh38	Loss	LCNL1 PTGDS
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	PRR31 LCNL1 CLIC3 ABCA2 C9orf142 PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	PRR31 LCNL1 CLIC3 FUT7 NPDC1 ABCA2 LRRC26 PTGDS MIR3621 C9orf139 ENTPD2 TMEM210 MAN1B1-AS1 UAP1L1 DPP7 MAN1B1 C9orf142 LOC101930307 GRIN1 SAPCD2
nsv615995	Chr.9:136976551 - 136978985 on Build GRCh38	Loss	PTGDS
nsv615993	Chr.9:136975638 - 136983246 on Build GRCh38	Gain	LCNL1 PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	LCNL1 C8G LCN10 ABCA2 CCDC183 MAMDC4 LOC100128593 TRAF2 C9orf142 EDF1 RABL6 PRR31 CCDC183-AS1 PHPT1 CLIC3 MIR4292 MIR4479 FBXW5 LCN8 LCN15 PTGDS C9orf172 LCN12 MIR6722 TMEM141 LCN6
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	LCNL1 C8G NOXA1 NPDC1 TRAF2 PNPLA7 C9orf173-AS1 MAN1B1-AS1 TPRN C9orf142 GRIN1 EDF1 PRR31 PHPT1 MIR4292 MIR4479 FBXW5 NSMF RNF224 FAM166A PTGDS NRARP NDOR1 UAP1L1 ENTPD8 FUT7 NELFB ABCA2 TMEM203 CCDC183 MIR7114 MAMDC4 CYSRT1 SSNA1 SLC34A3 TUBB4B RNF208 STPG3 C9orf139 TMEM210 MAN1B1 LOC101930307 EXD3 RABL6 CCDC183-AS1 ANAPC2 CLIC3 TOR4A LRRC26 C9orf172 LCN12 MIR3621 ENTPD2 DPP7 SAPCD2
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	PRR31 LCNL1 C8G CLIC3 FUT7 NPDC1 ABCA2 PTGDS LCN12 C9orf139 ENTPD2 MAN1B1-AS1 UAP1L1 DPP7 MAN1B1 C9orf142 LOC101930307 SAPCD2
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	LCNL1 C8G NPDC1 HSPC324 LOC100128593 PMPCA SNORA17A TRAF2 MIR4673 MAN1B1-AS1 C9orf142 GRIN1 MIR126 EDF1 AGPAT2 PRR31 PHPT1 MIR4292 MIR4479 C9orf163 EGFL7 FBXW5 LCN8 PTGDS SDCCAG3 NOTCH1 UAP1L1 MIR6722 TMEM141 SNHG7 LCN6 FAM69B SEC16A FUT7 LCN10 DNLZ SNAPC4 ABCA2 CCDC183 MAMDC4 MIR4674 C9orf139 TMEM210 MAN1B1 LOC101930307 RABL6 CCDC183-AS1 CLIC3 LRRC26 LCN15 LINC01451 NALT1 C9orf172 LCN12 MIR3621 SNORA17B ENTPD2 CARD9 DPP7 INPP5E SAPCD2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	LCNL1 C8G NPDC1 HSPC324 LOC100128593 SNORA17A TRAF2 C9orf173-AS1 MAN1B1-AS1 TPRN C9orf142 GRIN1 MIR126 EDF1 AGPAT2 PRR31 PHPT1 MIR4292 MIR4479 EGFL7 FBXW5 RNF224 LCN8 FAM166A PTGDS NRARP NDOR1 UAP1L1 MIR6722 TMEM141 SNHG7 LCN6 FAM69B FUT7 LCN10 NELFB ABCA2 TMEM203 CCDC183 MAMDC4 CYSRT1 SSNA1 SLC34A3 TUBB4B RNF208 STPG3 C9orf139 TMEM210 MAN1B1 LOC101930307 EXD3 RABL6 CCDC183-AS1 ANAPC2 CLIC3 TOR4A LRRC26 LCN15 LINC01451 C9orf172 LCN12 MIR3621 SNORA17B ENTPD2 DPP7 SAPCD2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding