Hs01492069_cn

• Gene Symbol: C21orf58
• Assay Reference Genome Location: Chr.21:46301872 on build GRCh38
• Cytoband: 21q22.3

Target Gene Details

• Entrez Gene ID: 54058
• Gene Name: chromosome 21 open reading frame 58
• Gene Aliases: -
• Location: Chr.21:46300426-46323899 on Build GRCh38
• Assay Gene Location: Within Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
C21orf58	NM_001286462.1			NP_001273391.1
	NM_001286463.1	7	1245	NP_001273392.1
	NM_001286476.1			NP_001273405.1
	NM_001286477.1	8	1886	NP_001273406.1
	NM_058180.4	8	2258	NP_478060.2
	XM_005261148.4			XP_005261205.1
	XM_006724018.3			XP_006724081.1
	XM_011529619.2			XP_011527921.1
	XM_011529620.2			XP_011527922.1
	XM_011529621.2	8	2241	XP_011527923.1
	XM_011529623.2	8	4246	XP_011527925.1
	XM_011529624.2	8	1121	XP_011527926.1
	XM_011529625.2	8	1395	XP_011527927.1
	XM_011529626.2	9	4592	XP_011527928.1
	XM_011529627.2	9	4672	XP_011527929.1
	XM_017028388.1	9	4423	XP_016883877.1
	XM_017028389.1			XP_016883878.1
	XM_017028390.1	9	2590	XP_016883879.1
	XM_017028391.1	8	2413	XP_016883880.1
	XM_017028392.1	10	1610	XP_016883881.1
	XM_017028393.1	9	1409	XP_016883882.1
	AK056387.1	8	2231
	AK096641.1	7	2162
	AK098098.1	7	1182	BAC05232.1
	AY039243.1			AAK72408.1
	AY039244.1			AAK72409.1
	BM475055.1
	CB305953.1

Target Gene Details

• Entrez Gene ID: 54059
• Gene Name: ybeY metallopeptidase (putative)
• Gene Aliases: C21orf57
• Location: Chr.21:46286056-46314188 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YBEY	XM_011529633.2			XP_011527935.1
	XM_017028394.1			XP_016883883.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv3547	Chr.21:46283787 - 46321516 on Build GRCh38	Insertion	MCM3AP C21orf58 YBEY
nsv519904	Chr.21:46163592 - 46461396 on Build GRCh38	Loss	DIP2A MCM3AP C21orf58 MCM3AP-AS1 PCNT YBEY LSS SPATC1L
nsv587980	Chr.21:46295382 - 46302616 on Build GRCh38	Loss	C21orf58 YBEY
nsv527355	Chr.21:46258860 - 46443112 on Build GRCh38	Gain	MCM3AP C21orf58 PCNT YBEY
nsv470910	Chr.21:45933861 - 46665076 on Build GRCh38	Gain	DIP2A-IT1 FTCD COL6A2 C21orf58 COL6A1 MCM3AP-AS1 LOC101928796 YBEY LSS PCBP3 SPATC1L S100B DIP2A MCM3AP PCNT PRMT2
nsv587975	Chr.21:46241321 - 46410929 on Build GRCh38	Gain	MCM3AP C21orf58 MCM3AP-AS1 PCNT YBEY
nsv1060978	Chr.21:46068159 - 46413726 on Build GRCh38	Gain	FTCD COL6A2 MCM3AP C21orf58 MCM3AP-AS1 PCNT YBEY LSS SPATC1L

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, endoribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

rRNA processing
proteolysis

Function(s)

metalloendopeptidase activity
metal ion binding