Hs01511075_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54143748 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Overlaps Exon 5 - Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AB014591.1
	AF180474.1			AAF29828.1
	AK160386.1	5	514	BAD18729.1
	AK300434.1
	BC016474.1			AAH16474.1
	BQ439042.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	TMC4 CNOT3 NDUFA3 TFPT LENG1 MBOAT7 PRPF31
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	OSCAR TMC4 CNOT3 NDUFA3 TSEN34 TFPT LENG1 MBOAT7 PRPF31
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	ZNF765 MIR520B TPM3P9 TSEN34 MIR519D ZNF813 MIR1283-1 MIR520G FAM90A27P ZNF331 ZNF761 PRPF31 MYADM MIR515-1 MIR524 CACNG6 LILRB5 MIR516A1 OSCAR MIR526A1 MIR518B MIR519B ZNF845 RPS9 MIR523 CACNG7 MIR518A1 PRKCG MIR518E LOC284379 VSTM1 MIR4752 MIR935 MIR522 MIR516B2 MIR517B NLRP12 CACNG8 MIR518A2 ZNF665 MIR520A ZNF818P CNOT3 MIR1283-2 MIR519C MIR527 MIR518D TFPT MIR520H MIR498 MIR520C MBOAT7 TARM1 VN1R4 TMC4 BIRC8 MIR373 MIR371A NDUFA3 MIR519E ZNF525 MIR512-1 MIR1323 MIR519A2 LILRB3 LILRB2 MIR519A1 MIR520D MIR525 ZNF677 MIR371B MIR521-1 MIR512-2 LENG1 MIR518F MIR516A2 MIR517C MIR520E MIR520F MIR516B1 LOC105372457 LILRA5 LILRA6 MIR526A2 MIR517A MIR518C DPRX MIR526B VN1R2 MIR521-2 MIR515-2 MIR372

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding