Hs01515372_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137180281 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	10	1863	NP_037498.1
	AB037827.1	8	1039	BAA92644.1
	AF191337.1	10	1790	AAF05751.1
	AK294601.1	10	1818
	BC001579.1	8	1055	AAH01579.1
	BC009487.2	6	654	AAH09487.2
	BC032503.1	10	1795	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	RNF208 TPRN MIR3621 TMEM210 RNF224 DPP7 LOC101930307 TMEM203 LRRC26 CYSRT1 MAN1B1-AS1 GRIN1 ANAPC2 SLC34A3 SSNA1 NDOR1 UAP1L1 MAN1B1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	C9orf173-AS1 RNF208 TPRN EXD3 RNF224 TMEM203 TUBB4B NRARP STPG3 CYSRT1 FAM166A ANAPC2 SLC34A3 NELFB SSNA1 NDOR1 TOR4A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	EDF1 LCNL1 CCDC183-AS1 STPG3 TRAF2 PRR31 LCN12 GRIN1 TOR4A NPDC1 C9orf173-AS1 C9orf139 TPRN NOXA1 PTGDS DPP7 LRRC26 C9orf172 FUT7 C8G MAMDC4 CYSRT1 FAM166A PHPT1 ABCA2 EXD3 MIR3621 MIR7114 TMEM210 TUBB4B NSMF NRARP MAN1B1-AS1 ANAPC2 SLC34A3 SSNA1 SAPCD2 UAP1L1 RABL6 CCDC183 RNF208 RNF224 ENTPD8 CLIC3 FBXW5 LOC101930307 MIR4479 TMEM203 MIR4292 PNPLA7 C9orf142 ENTPD2 NELFB NDOR1 MAN1B1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	C9orf173-AS1 RNF208 TPRN EXD3 MIR3621 TMEM210 RNF224 TMEM203 LRRC26 TUBB4B NRARP STPG3 CYSRT1 FAM166A GRIN1 ANAPC2 SLC34A3 NELFB SSNA1 NDOR1 TOR4A
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	C9orf173-AS1 RNF208 TPRN EXD3 NOXA1 MIR3621 TMEM210 RNF224 ENTPD8 TMEM203 LRRC26 TUBB4B NRARP STPG3 CYSRT1 FAM166A GRIN1 ANAPC2 SLC34A3 NELFB SSNA1 NDOR1 TOR4A
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	C9orf139 MIR3621 TMEM210 DPP7 LOC101930307 LRRC26 FUT7 MAN1B1-AS1 ENTPD2 GRIN1 ANAPC2 SSNA1 SAPCD2 UAP1L1 MAN1B1 NPDC1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	EDF1 SNORA17A LCNL1 CCDC183-AS1 STPG3 TRAF2 PRR31 LCN12 EGFL7 GRIN1 TOR4A SNORA17B NPDC1 C9orf173-AS1 C9orf139 TPRN PTGDS DPP7 LRRC26 C9orf172 FUT7 C8G MAMDC4 CYSRT1 SNHG7 FAM166A PHPT1 ABCA2 HSPC324 LCN6 EXD3 MIR3621 LOC100128593 TMEM210 LCN10 AGPAT2 TUBB4B FAM69B LINC01451 NRARP MIR6722 MAN1B1-AS1 LCN8 ANAPC2 SLC34A3 SSNA1 SAPCD2 UAP1L1 LCN15 RABL6 CCDC183 RNF208 RNF224 TMEM141 CLIC3 FBXW5 LOC101930307 MIR4479 TMEM203 MIR4292 C9orf142 MIR126 ENTPD2 NELFB NDOR1 MAN1B1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity