Hs01577538_cn

• Gene Symbol: DSTYK
• Assay Reference Genome Location: Chr.1:205142690 on build GRCh38
• Cytoband: 1q32.1

Target Gene Details

• Entrez Gene ID: 25778
• Gene Name: dual serine/threonine and tyrosine protein kinase
• Gene Aliases: CAKUT1, DustyPK, HDCMD38P, RIP5, RIPK5
• Location: Chr.1:205142497-205211599 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DSTYK	NM_015375.2	13	7722	NP_056190.1
	NM_199462.2	12	7587	NP_955749.1
	XM_011509392.2	13	7653	XP_011507694.1
	XM_011509393.2	14	7616	XP_011507695.1
	XM_011509394.2	12	7124	XP_011507696.1
	AJ420466.1	1	547
	AY429674.1	13	7694	AAS55390.1
	BU528180.1	1	670

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv563n100	Chr.1:205101394 - 205152107 on Build GRCh38	Gain	DSTYK RBBP5
nsv468016	Chr.1:205114992 - 205193929 on Build GRCh38	Loss	DSTYK RBBP5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

peptidyl-tyrosine phosphorylation
positive regulation of kinase activity
cellular response to fibroblast growth factor stimulus
positive regulation of fibroblast growth factor receptor signaling pathway
positive regulation of ERK1 and ERK2 cascade

Function(s)

protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
ATP binding