Hs01612670_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175316 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	12	2250	NP_037498.1
	AB037827.1	10	1426	BAA92644.1
	AF191337.1	12	2177	AAF05751.1
	AK294601.1
	BC001579.1	10	1442	AAH01579.1
	BC009487.2	8	1041	AAH09487.2
	BC032503.1	12	2182	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	GRIN1 RNF208 LRRC26 NDOR1 MIR3621 CYSRT1 ANAPC2 SSNA1 UAP1L1 LOC101930307 TMEM203 DPP7 RNF224 TMEM210 TPRN MAN1B1 SLC34A3 MAN1B1-AS1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF208 NRARP NDOR1 TUBB4B C9orf173-AS1 CYSRT1 ANAPC2 SSNA1 TMEM203 EXD3 RNF224 TPRN NELFB STPG3 SLC34A3 FAM166A TOR4A
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	GRIN1 LRRC26 ENTPD8 NDOR1 MIR3621 NOXA1 UAP1L1 EXD3 RNF224 FBXW5 MAN1B1 MAMDC4 TOR4A TRAF2 MAN1B1-AS1 RNF208 SAPCD2 CCDC183 ABCA2 ENTPD2 PRR31 TMEM203 TMEM210 PTGDS SLC34A3 FAM166A NPDC1 C9orf142 C9orf173-AS1 CYSRT1 ANAPC2 SSNA1 CLIC3 LOC101930307 LCN12 TPRN C9orf139 C9orf172 STPG3 LCNL1 MIR7114 NRARP CCDC183-AS1 RABL6 PHPT1 C8G NSMF FUT7 TUBB4B DPP7 MIR4479 EDF1 MIR4292 NELFB PNPLA7
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	GRIN1 RNF208 NRARP LRRC26 NDOR1 MIR3621 TUBB4B C9orf173-AS1 CYSRT1 ANAPC2 SSNA1 TMEM203 EXD3 RNF224 TMEM210 TPRN NELFB STPG3 SLC34A3 FAM166A TOR4A
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	GRIN1 RNF208 NRARP LRRC26 ENTPD8 NDOR1 MIR3621 TUBB4B C9orf173-AS1 CYSRT1 ANAPC2 SSNA1 NOXA1 TMEM203 EXD3 RNF224 TMEM210 TPRN NELFB STPG3 SLC34A3 FAM166A TOR4A
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	GRIN1 LRRC26 SAPCD2 MIR3621 FUT7 ANAPC2 SSNA1 ENTPD2 UAP1L1 LOC101930307 DPP7 TMEM210 C9orf139 MAN1B1 NPDC1 MAN1B1-AS1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	GRIN1 LRRC26 HSPC324 NDOR1 MIR3621 SNORA17B SNORA17A MIR6722 UAP1L1 EXD3 RNF224 LCN15 FBXW5 MAN1B1 MAMDC4 TOR4A TRAF2 MAN1B1-AS1 RNF208 SNHG7 SAPCD2 CCDC183 ABCA2 ENTPD2 FAM69B PRR31 TMEM203 TMEM210 PTGDS SLC34A3 FAM166A NPDC1 C9orf142 C9orf173-AS1 TMEM141 CYSRT1 ANAPC2 SSNA1 CLIC3 LOC101930307 LCN12 TPRN LCN8 C9orf139 C9orf172 LCN10 AGPAT2 STPG3 LCNL1 NRARP CCDC183-AS1 RABL6 PHPT1 LINC01451 C8G LOC100128593 FUT7 TUBB4B DPP7 MIR4479 EDF1 MIR126 EGFL7 MIR4292 NELFB LCN6

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity