Hs01616775_cn

• Gene Symbol: DHX58
• Assay Reference Genome Location: Chr.17:42105061 on build GRCh38
• Cytoband: 17q21.2

Target Gene Details

• Entrez Gene ID: 79132
• Gene Name: DEXH-box helicase 58
• Gene Aliases: D11LGP2, D11lgp2e, LGP2, RLR-3
• Location: Chr.17:42101404-42112733 on Build GRCh38
• Assay Gene Location: Overlaps Intron 10 - Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DHX58	NM_024119.2			NP_077024.2
	XM_017025059.1			XP_016880548.1
	XM_017025060.1			XP_016880549.1
	AK021416.1			BAB13818.1
	AK097669.1
	AK225549.1
	AK296840.1
	AK300900.1
	BC014949.1			AAH14949.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1056904	Chr.17:42025823 - 42363204 on Build GRCh38	Gain	KCNH4 ZNF385C GHDC DHX58 STAT5A HCRT HSPB9 STAT5B KAT2A STAT3 RAB5C

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

response to virus
negative regulation of type I interferon production
positive regulation of type I interferon production
negative regulation of MDA-5 signaling pathway
negative regulation of RIG-I signaling pathway
innate immune response
regulation of innate immune response
negative regulation of innate immune response
defense response to virus
positive regulation of MDA-5 signaling pathway
positive regulation of RIG-I signaling pathway

Function(s)

DNA binding
double-stranded RNA binding
single-stranded RNA binding
helicase activity
protein binding
ATP binding
zinc ion binding