Hs01659715_cn

• Gene Symbol: PIAS2
• Assay Reference Genome Location: Chr.18:46821021 on build GRCh38
• Cytoband: 18q21.1

Target Gene Details

• Entrez Gene ID: 9063
• Gene Name: protein inhibitor of activated STAT 2
• Gene Aliases: ARIP3, DIP, MIZ, MIZ1, PIASX, PIASX-ALPHA, PIASX-BETA, SIZ2, ZMIZ4
• Location: Chr.18:46803224-46920167 on Build GRCh38
• Assay Gene Location: Overlaps Intron 19 - Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIAS2	NM_001324046.1			NP_001310975.1
	NM_001324047.1			NP_001310976.1
	NM_001324048.1			NP_001310977.1
	NM_001324049.1			NP_001310978.1
	NM_001324051.1			NP_001310980.1
	NM_001324052.1			NP_001310981.1
	NM_001324053.1			NP_001310982.1
	NM_001324054.1			NP_001310983.1
	NM_004671.4			NP_004662.2
	NM_173206.3			NP_775298.1
	NR_136684.1
	NR_136685.1
	XM_005258377.3			XP_005258434.1
	XM_005258379.3			XP_005258436.1
	XM_006722571.3			XP_006722634.1
	XM_006722572.3			XP_006722635.1
	XM_006722573.2			XP_006722636.1
	XM_011526258.2			XP_011524560.1
	XM_011526259.2			XP_011524561.1
	XM_017026068.1			XP_016881557.1
	XM_017026069.1			XP_016881558.1
	XM_017026070.1			XP_016881559.1
	XM_017026071.1			XP_016881560.1
	XM_017026072.1			XP_016881561.1
	AF077953.1			AAC36704.1
	AF077954.1			AAC36705.1
	AK294801.1
	AK308143.1
	AW016227.1
	BC015190.1			AAH15190.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428355	Chr.18:46580218 - 46826322 on Build GRCh38	Gain	ST8SIA5 LOXHD1 PIAS2
nsv9629	Chr.18:46684730 - 47231140 on Build GRCh38	Gain+Loss	IER3IP1 HDHD2 TCEB3B SKOR2 LOC107983955 TCEB3CL TCEB3C KATNAL2 TCEB3CL2 ST8SIA5 PIAS2
dgv614e214	Chr.18:46702717 - 46833888 on Build GRCh38	Gain	ST8SIA5 PIAS2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
protein sumoylation
androgen receptor signaling pathway
regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of androgen receptor signaling pathway

Function(s)

DNA binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
ligase activity
SUMO transferase activity
ubiquitin protein ligase binding
androgen receptor binding
SUMO ligase activity