Hs01685871_cn

• Gene Symbol: JMJD7-PLA2G4B
• Assay Reference Genome Location: Chr.15:41841286 on build GRCh38
• Cytoband: 15q15.1

Target Gene Details

• Entrez Gene ID: 8681
• Gene Name: JMJD7-PLA2G4B readthrough
• Gene Aliases: HsT16992, cPLA2-beta
• Location: Chr.15:41828085-41848148 on Build GRCh38
• Assay Gene Location: Overlaps Exon 11 - Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
JMJD7-PLA2G4B	NM_001198588.1			NP_001185517.1
	NM_005090.3			NP_005081.1
	AB209150.1			BAD92387.1
	AF065215.1			AAC78836.1
	AF065216.1
	AF121908.1			AAD32135.1
	DQ523799.1
	DQ523800.1

Target Gene Details

• Entrez Gene ID: 100137049
• Gene Name: phospholipase A2 group IVB
• Gene Aliases: HsT16992, cPLA2-beta
• Location: Chr.15:41838813-41848148 on Build GRCh38
• Assay Gene Location: Overlaps Exon 6 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PLA2G4B	NM_001114633.1			NP_001108105.1
	AK299419.1
	AK310651.1	6	549
	DA250544.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv9244	Chr.15:41818514 - 41916607 on Build GRCh38	Gain	EHD4 PLA2G4B JMJD7-PLA2G4B MAPKBP1 LOC105370792 MIR4310 JMJD7 SPTBN5
nsv1035998	Chr.15:41806698 - 42142056 on Build GRCh38	Gain	EHD4-AS1 PLA2G4D PLA2G4B JMJD7-PLA2G4B MAPKBP1 MIR4310 SPTBN5 EHD4 PLA2G4E-AS1 PLA2G4F PLA2G4E LOC105370792 JMJD7
nsv1050892	Chr.15:41836657 - 41894284 on Build GRCh38	Gain	PLA2G4B JMJD7-PLA2G4B LOC105370792 MIR4310 JMJD7 SPTBN5
nsv1506	Chr.15:41824733 - 41857173 on Build GRCh38	Insertion	PLA2G4B JMJD7-PLA2G4B MAPKBP1 JMJD7 SPTBN5
nsv952613	Chr.15:41816803 - 41884902 on Build GRCh38	Deletion	PLA2G4B JMJD7-PLA2G4B MAPKBP1 MIR4310 JMJD7 SPTBN5
nsv517631	Chr.15:41804728 - 41895294 on Build GRCh38	Loss	PLA2G4B JMJD7-PLA2G4B MAPKBP1 LOC105370792 MIR4310 JMJD7 SPTBN5
dgv2582n100	Chr.15:41791376 - 41900562 on Build GRCh38	Gain	EHD4 PLA2G4B JMJD7-PLA2G4B MAPKBP1 LOC105370792 MIR4310 JMJD7 SPTBN5

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phospholipase

Gene Ontology Categories:

Process(es)

phospholipid metabolic process
phosphatidic acid biosynthetic process
inflammatory response
parturition
arachidonic acid metabolic process
calcium-mediated signaling
phosphatidylglycerol acyl-chain remodeling
phosphatidylserine acyl-chain remodeling
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
IRE1-mediated unfolded protein response
glycerophospholipid catabolic process

Function(s)

lysophospholipase activity
phospholipase A2 activity
calcium ion binding
calcium-dependent phospholipid binding
phosphatidylcholine 1-acylhydrolase activity
calcium-dependent phospholipase A2 activity