Hs01704480_cn

• Gene Symbol: MARS
• Assay Reference Genome Location: Chr.12:57512771 on build GRCh38
• Cytoband: 12q13.3

Target Gene Details

• Entrez Gene ID: 4141
• Gene Name: methionyl-tRNA synthetase
• Gene Aliases: CMT2U, ILFS2, ILLD, METRS, MRS, MTRNS, SPG70
• Location: Chr.12:57487953-57516655 on Build GRCh38
• Assay Gene Location: Overlaps Intron 14 - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MARS	NM_004990.3			NP_004981.2
	XM_006719398.3			XP_006719461.1
	AK092986.1			BAC04011.1
	AK122956.1
	AK222767.1			BAD96487.1
	AK290857.1
	AK293945.1
	BC002384.2			AAH02384.1
	BC006328.2			AAH06328.1
	BC011639.2			AAH11639.1
	BC011849.2			AAH11849.1
	BC015011.1			AAH15011.1
	BT007338.1			AAP36002.1
	D84224.1			BAA95668.1
	X94754.1			CAA64381.1
	Z49216.1			CAA89153.1

Target Gene Details

• Entrez Gene ID: 102465454
• Gene Name: microRNA 6758
• Gene Aliases: hsa-mir-6758
• Location: Chr.12:57512688-57512750 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR6758	NR_106816.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428283	Chr.12:57435950 - 57608085 on Build GRCh38	Gain	INHBC KIF5A MIR6758 DTX3 INHBE MIR616 MARS MBD6 DDIT3 GLI1 DCTN2 PIP4K2C ARHGAP9
nsv559034	Chr.12:57466149 - 57618450 on Build GRCh38	Loss	KIF5A MIR6758 LOC101927583 DTX3 MIR616 ARHGEF25 MARS MBD6 DDIT3 GLI1 DCTN2 PIP4K2C ARHGAP9
nsv469411	Chr.12:57450266 - 57527405 on Build GRCh38	Loss	INHBC MARS MIR6758 INHBE MIR616 MBD6 DDIT3 GLI1 ARHGAP9
esv3419248	Chr.12:57511702 - 57513300 on Build GRCh38	Duplication	MARS MIR6758
nsv482992	Chr.12:56206217 - 57706217 on Build GRCh38	Gain+Loss	KIF5A DTX3 STAT6 MARS MIP GLS2 RNF41 NXPH4 SNORD59A LRP1 RBMS2 NEMP1 PTGES3 ATP5B MIR616 OS9 PRIM1 SNORD59B SNORA105C ZBTB39 NACA RDH16 STAC3 TIMELESS DDIT3 B4GALNT1 APOF CS SDR9C7 INHBC COQ10A SPRYD4 ANKRD52 MIR6758 LOC101927583 LRP1-AS NAB2 SLC39A5 ARHGEF25 CNPY2 HSD17B6 MBD6 GLI1 NDUFA4L2 DCTN2 ARHGAP9 STAT2 MIR1228 SLC26A10 IL23A TAC3 R3HDM2 INHBE NABP2 BAZ2A GPR182 SHMT2 PAN2 HBCBP MYO1A PIP4K2C

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

aminoacyl-tRNA synthetase

Gene Ontology Categories:

Process(es)

tRNA aminoacylation for protein translation
methionyl-tRNA aminoacylation

Function(s)

tRNA binding
methionine-tRNA ligase activity
ATP binding