Hs01791405_cn

• Gene Symbol: PNPO
• Assay Reference Genome Location: Chr.17:47948895 on build GRCh38
• Cytoband: 17q21.32

Target Gene Details

• Entrez Gene ID: 55163
• Gene Name: pyridoxamine 5'-phosphate oxidase
• Gene Aliases: HEL-S-302, PDXPO
• Location: Chr.17:47941523-47949308 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PNPO	NM_018129.3	7	3052	NP_060599.1
	XM_005257500.3	7	3242	XP_005257557.1
	XM_011524968.2	6	2825	XP_011523270.1
	XM_017024813.1	7	2840	XP_016880302.1
	CB853441.1	1	431

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv1000014	Chr.17:47941862 - 47952091 on Build GRCh38	Deletion	PNPO PRR15L
nsv518892	Chr.17:47810585 - 47952066 on Build GRCh38	Loss	SP6 PNPO LOC102724532 SP2 MRPL10 SCRN2 PRR15L SP2-AS1 OSBPL7 LRRC46

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

positive regulation of defense response to virus by host
pyridoxine biosynthetic process
vitamin B6 metabolic process
pyridoxal phosphate biosynthetic process
oxidation-reduction process
mitophagy in response to mitochondrial depolarization
xenophagy

Function(s)

pyridoxamine-phosphate oxidase activity
FMN binding