Hs01852677_cn

• Gene Symbol: POLR3C
• Assay Reference Genome Location: Chr.1:145825883 on build GRCh38
• Cytoband: 1q21.1

Target Gene Details

• Entrez Gene ID: 10623
• Gene Name: RNA polymerase III subunit C
• Gene Aliases: RPC3, RPC62
• Location: Chr.1:145823183-145844402 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3C	NM_001303456.1	2	230	NP_001290385.1
	NM_006468.7	2	428	NP_006459.3
	XM_005272927.3	2	1314	XP_005272984.1
	XM_005272928.3	2	230	XP_005272985.1
	XM_011509078.2	2	184	XP_011507380.1
	AK223413.1	2	191	BAD97133.1
	AY091463.1	1	125	AAM12033.1
	BC002586.1	2	277	AAH02586.1
	BC004424.1	2	321	AAH04424.1
	BI831011.1	2	428
	DA816269.1	2	230
	U93867.1	2	261	AAB63675.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv331n100	Chr.1:145642988 - 145827134 on Build GRCh38	Gain	RNF115 POLR3C CD160 PDZK1 GPR89A
esv3587420	Chr.1:145824369 - 145905171 on Build GRCh38	Gain	PIAS3 POLR3C ITGA10 MIR6736 ANKRD35 NUDT17
nsv831381	Chr.1:145784568 - 145960930 on Build GRCh38	Gain	RNF115 PEX11B ANKRD34A ITGA10 RBM8A ANKRD35 NUDT17 POLR3GL GNRHR2 PIAS3 POLR3C MIR6736 LIX1L

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

regulation of transcription from RNA polymerase III promoter
transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of interferon-beta production
innate immune response
positive regulation of innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
DNA binding
DNA-directed RNA polymerase activity
protein binding