Hs01853411_cn

• Gene Symbol: IFIH1
• Assay Reference Genome Location: Chr.2:162267515 on build GRCh38
• Cytoband: 2q24.2

Target Gene Details

• Entrez Gene ID: 64135
• Gene Name: interferon induced with helicase C domain 1
• Gene Aliases: AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2, SGMRT1
• Location: Chr.2:162267079-162318708 on Build GRCh38
• Assay Gene Location: Overlaps Intron 14 - Exon 15

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IFIH1	NM_022168.3			NP_071451.2
	AF095844.1			AAG34368.1
	AK056293.1			BAB71141.1
	AK292941.1
	AK314611.1
	AY017378.1			AAG54076.1
	BC111750.1			AAI11751.1
	BQ772836.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv583520	Chr.2:162267541 - 162611723 on Build GRCh38	Loss	KCNH7 GCA IFIH1
dgv749e214	Chr.2:162204243 - 162287181 on Build GRCh38	Gain	FAP IFIH1
nsv834440	Chr.2:162145758 - 162318828 on Build GRCh38	Gain	GCA FAP LOC101929532 GCG IFIH1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

detection of virus
response to virus
protein sumoylation
negative regulation of type I interferon production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
regulation of type III interferon production
cytoplasmic pattern recognition receptor signaling pathway in response to virus
MDA-5 signaling pathway
innate immune response

Function(s)

DNA binding
double-stranded RNA binding
single-stranded RNA binding
helicase activity
protein binding
ATP binding
zinc ion binding
ribonucleoprotein complex binding