Hs01872777_cn

• Gene Symbol: TBCD
• Assay Reference Genome Location: Chr.17:82830109 on build GRCh38
• Cytoband: 17q25.3

Target Gene Details

• Entrez Gene ID: 6904
• Gene Name: tubulin folding cofactor D
• Gene Aliases: SSD-1, tfcD
• Location: Chr.17:82752048-82943186 on Build GRCh38
• Assay Gene Location: Within Intron 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TBCD	NM_005993.4			NP_005984.3
	XM_005256396.4			XP_005256453.1
	XM_006722290.2			XP_006722353.1
	XM_011523589.1			XP_011521891.1
	XM_011523590.1			XP_011521892.1
	XM_011523591.1			XP_011521893.1
	XM_011523593.1			XP_011521895.1
	XM_017024987.1			XP_016880476.1
	XM_017024988.1			XP_016880477.1
	XM_017024990.1			XP_016880479.1
	AB023205.1
	AJ006417.1			CAA07022.1
	AK091959.1			BAC03777.1
	AK293471.1
	AL133562.1			CAB63716.1
	BC003094.1			AAH03094.1

Target Gene Details

• Entrez Gene ID: 79755
• Gene Name: zinc finger protein 750
• Gene Aliases: ZFP750
• Location: Chr.17:82829434-82840055 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZNF750	NM_024702.2	3	2516	NP_078978.2
	AK023903.1	3	2485	BAB14718.1
	AK301690.1	4	1292
	BC109036.1	3	2475	AAI09037.1
	BC109037.1	3	2475	AAI09038.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1067553	Chr.17:82530808 - 83091923 on Build GRCh38	Loss	METRNL FN3KRP FN3K LOC105371944 ZNF750 WDR45B LOC105376791 MIR4525 FOXK2 LOC101929552 B3GNTL1 RAB40B TBCD
nsv833575	Chr.17:82660876 - 82847512 on Build GRCh38	Loss	LOC105376791 FN3KRP MIR4525 FN3K LOC101929552 ZNF750 RAB40B TBCD
nsv428351	Chr.17:81152631 - 83064073 on Build GRCh38	Gain	PCYT2 LINC00482 MAFG-AS1 OXLD1 MCRIP1 BAHCC1 C17orf62 FASN MIR4740 SLC16A3 LOC105376790 NPLOC4 MYADML2 AATK-AS1 PDE6G TBCD FSCN2 GCGR PPP1R27 MAFG HGS GPS1 WDR45B LRRC45 TMEM105 P4HB LOC105376791 CEP131 RAC3 SECTM1 C17orf89 MIR6787 B3GNTL1 RAB40B AATK OGFOD3 LOC105371925 DCXR LOC101929511 LOC105371944 ZNF750 DUS1L PYCR1 CCDC57 CCDC137 LOC100130370 NPB MIR4525 ALYREF SLC38A10 FOXK2 LOC101929552 TEPSIN FAAP100 ARL16 ARHGDIA MIR6786 HEXDC STRA13 NARF SLC25A10 CSNK1D FN3KRP FN3K RFNG ASPSCR1 MRPL12 UTS2R CD7 SIRT7 ACTG1 TEX19 MIR3186 NOTUM TSPAN10 SNORD134 ANAPC11
nsv1057589	Chr.17:82815790 - 82852057 on Build GRCh38	Loss	ZNF750 TBCD
nsv833576	Chr.17:82769162 - 82847512 on Build GRCh38	Gain	ZNF750 TBCD
esv2762577	Chr.17:82244836 - 82838431 on Build GRCh38	Gain+Loss	CSNK1D OGFOD3 FN3KRP FN3K C17orf62 LOC101929511 ZNF750 WDR45B UTS2R CD7 LOC105376791 LOC105376790 TEX19 MIR4525 FOXK2 LOC101929552 SECTM1 HEXDC RAB40B NARF TBCD
esv21913	Chr.17:81828123 - 83103548 on Build GRCh38	Gain+Loss	PCYT2 MAFG-AS1 METRNL MCRIP1 C17orf62 FASN SLC16A3 LOC105376790 MYADML2 TBCD PPP1R27 MAFG GPS1 WDR45B LRRC45 P4HB LOC105376791 RAC3 SECTM1 MIR6787 B3GNTL1 RAB40B OGFOD3 DCXR LOC101929511 LOC105371944 ZNF750 DUS1L PYCR1 CCDC57 NPB MIR4525 ALYREF FOXK2 LOC101929552 ARHGDIA HEXDC STRA13 NARF CSNK1D FN3KRP FN3K RFNG ASPSCR1 UTS2R CD7 SIRT7 TEX19 NOTUM SNORD134 ANAPC11

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
transcription from RNA polymerase II promoter
epidermis development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter

Function(s)

GTPase activator activity
protein binding
beta-tubulin binding
chaperone binding
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
metal ion binding