Hs01892235_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175833 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 10 - Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	CYSRT1 MAN1B1-AS1 MAN1B1 TMEM210 RNF208 RNF224 GRIN1 TMEM203 LRRC26 LOC101930307 NDOR1 UAP1L1 SLC34A3 SSNA1 TPRN DPP7 ANAPC2 MIR3621
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	CYSRT1 TOR4A STPG3 RNF208 FAM166A RNF224 EXD3 NELFB C9orf173-AS1 TMEM203 NDOR1 SLC34A3 SSNA1 NRARP TPRN ANAPC2 TUBB4B
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TOR4A NPDC1 RNF208 ENTPD2 C9orf139 NELFB PNPLA7 UAP1L1 TPRN ANAPC2 TUBB4B PTGDS MIR3621 MIR7114 MAN1B1 EDF1 TMEM210 FAM166A MIR4479 EXD3 ABCA2 C9orf173-AS1 CLIC3 LOC101930307 CCDC183 C9orf172 SLC34A3 SAPCD2 MAN1B1-AS1 STPG3 CCDC183-AS1 LCNL1 GRIN1 LCN12 MAMDC4 TRAF2 TMEM203 C8G NSMF MIR4292 SSNA1 NRARP PRR31 DPP7 C9orf142 RABL6 CYSRT1 ENTPD8 FBXW5 RNF224 PHPT1 FUT7 LRRC26 NDOR1 NOXA1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	CYSRT1 TOR4A STPG3 TMEM210 RNF208 FAM166A RNF224 EXD3 GRIN1 NELFB C9orf173-AS1 TMEM203 LRRC26 NDOR1 SLC34A3 SSNA1 NRARP TPRN ANAPC2 TUBB4B MIR3621
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	CYSRT1 TOR4A STPG3 ENTPD8 TMEM210 RNF208 FAM166A RNF224 EXD3 GRIN1 NELFB C9orf173-AS1 TMEM203 LRRC26 NDOR1 NOXA1 SLC34A3 SSNA1 NRARP TPRN ANAPC2 TUBB4B MIR3621
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	MAN1B1-AS1 NPDC1 MAN1B1 TMEM210 ENTPD2 C9orf139 GRIN1 FUT7 LRRC26 LOC101930307 UAP1L1 SSNA1 DPP7 SAPCD2 ANAPC2 MIR3621
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	TOR4A NPDC1 MIR6722 RNF208 ENTPD2 C9orf139 NELFB SNORA17B LOC100128593 UAP1L1 LINC01451 TPRN ANAPC2 TUBB4B PTGDS MIR3621 MAN1B1 EDF1 TMEM210 FAM166A MIR4479 EXD3 ABCA2 C9orf173-AS1 CLIC3 LOC101930307 CCDC183 C9orf172 EGFL7 SLC34A3 LCN8 SAPCD2 TMEM141 MAN1B1-AS1 STPG3 SNORA17A CCDC183-AS1 LCNL1 FAM69B GRIN1 LCN12 MAMDC4 TRAF2 HSPC324 TMEM203 C8G MIR4292 SNHG7 SSNA1 NRARP PRR31 DPP7 C9orf142 RABL6 LCN6 CYSRT1 FBXW5 LCN10 RNF224 PHPT1 FUT7 MIR126 LRRC26 NDOR1 AGPAT2 LCN15

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity