Hs01926839_cn

• Gene Symbol: POLR1A
• Assay Reference Genome Location: Chr.2:86026517 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 25885
• Gene Name: RNA polymerase I subunit A
• Gene Aliases: A190, AFDCIN, RPA1, RPA194, RPO1-4, RPO14
• Location: Chr.2:86026328-86106155 on Build GRCh38
• Assay Gene Location: Within Exon 34

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR1A	NM_015425.4	34	6448	NP_056240.2
	AK025568.1	11	2627	BAB15171.1
	AK294447.1	23	3708
	AL117467.1	3	1195	CAB55942.1
	BC017115.1	11	2633

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2751903	Chr.2:86026419 - 86278330 on Build GRCh38	Gain	PTCD3 MIR4779 SNORD94 POLR1A IMMT MRPL35 REEP1

More Information

Additional Information:

For this assay, SNP(s) [rs114947690] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
positive regulation of gene expression, epigenetic

Function(s)

RNA polymerase I activity
DNA binding
protein binding
zinc ion binding