Hs01932602_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37135341 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3			NP_000869.1
	AK312860.1
	BC025691.1			AAH25691.1
	CR456506.1			CAG30392.1
	M26062.1			AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	LOC101927051 SH3BP1 LOC102724378 LGALS1 TST CARD10 LOC100506271 TMPRSS6 IL2RB ELFN2 MPST GGA1 KCTD17 LGALS2 PDXP TEX33 SSTR3 C1QTNF6 MFNG CYTH4 TRIOBP RAC2 NOL12 CDC42EP1
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	LL22NC01-81G9.3 KCTD17 TST TEX33 TMPRSS6 IL2RB MPST
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	LL22NC01-81G9.3 KCTD17 TST TEX33 TMPRSS6 C1QTNF6 IL2RB MPST
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	LL22NC01-81G9.3 KCTD17 TST TEX33 TMPRSS6 IL2RB MPST
nsv588986	Chr.22:37133758 - 37145791 on Build GRCh38	Gain	IL2RB

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding