Hs01982150_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130764170 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	2	2272	NP_001098663.1
	NM_001105194.1	2	2208	NP_001098664.1
	NM_001105195.1	2	2205	NP_001098665.1
	NM_152698.2	2	2288	NP_689911.2
	XM_011510793.2	2	3314	XP_011509095.1
	AK095696.1	2	2252	BAC04612.1
	AK289525.1	2	2357
	AK291424.1	2	2252
	BC113445.1	2	2165
	BC113447.1	2	2165
	BC143806.1	2	2162

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	POTEJ POTEE POTEI CFC1 CYP4F30P GPR148 FAM168B LOC440910 PLEKHB2 ARHGEF4 AMER3 TISP43
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	POTEE POTEI CYP4F30P GPR148 FAM168B LOC440910 PLEKHB2 ARHGEF4 AMER3
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	POTEE POTEKP LOC150776 FAM168B NOC2LP2 WTH3DI POTEJ POTEI CYP4F30P GPR148 LOC440910 PLEKHB2 TUBA3D ARHGEF4 MZT2A CCDC74A MIR4784 AMER3 LINC01120
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	POTEI GPR148 ARHGEF4 AMER3
dgv4075n100	Chr.2:130720375 - 131521740 on Build GRCh38	Gain	POTEE LOC150776 FAM168B NOC2LP2 WTH3DI POTEI GPR148 LOC440910 PLEKHB2 TUBA3D ARHGEF4 MZT2A MIR4784 AMER3 LINC01120
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	POTEI GPR148 FAM168B PLEKHB2 ARHGEF4 AMER3
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	POTEE POTEI CYP4F30P GPR148 FAM168B LOC440910 PLEKHB2 ARHGEF4 AMER3
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	POTEI GPR148 FAM168B PLEKHB2 ARHGEF4 AMER3
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	POTEE LOC150776 FAM168B NOC2LP2 WTH3DI POTEI GPR148 LOC440910 PLEKHB2 TUBA3D ARHGEF4 MZT2A CCDC74A MIR4784 AMER3 LINC01120
nsv10175	Chr.2:130762563 - 130766308 on Build GRCh38	Loss	POTEI AMER3
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	POTEE LOC150776 FAM168B NOC2LP2 WTH3DI POTEJ POTEI CYP4F30P GPR148 LOC440910 PLEKHB2 TUBA3D ARHGEF4 MZT2A MIR4784 AMER3 LINC01120
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	GPR39 FAM168B CFC1B MED15P9 LOC389033 CFC1 LOC440910 PLEKHB2 PTPN18 LOC646743 TUBA3D MIR4784 AMER3 TUBA3E CYP4F62P LOC107985778 ZNF806 POTEI CYP4F30P SMPD4 ARHGEF4 NOC2LP1 RAB6C LINC01120 FAM201B ANKRD30BL FAR2P2 C2orf27B WTH3DI MIR663B CCDC74A LOC100507460 POTEF IMP4 POTEE POTEKP LOC150776 CCDC74B NOC2LP2 MZT2B LOC101927924 TISP43 CCDC115 RAB6C-AS1 POTEJ FAR2P1 C2orf27A GPR148 LINC01087 MZT2A
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	FAR2P2 CFC1B MED15P9 LOC389033 CFC1 PTPN18 LOC646743 AMER3 TUBA3E POTEF IMP4 CCDC74B CYP4F62P LOC107985778 MZT2B LOC101927924 TISP43 CCDC115 RAB6C-AS1 POTEJ FAR2P1 POTEI CYP4F30P GPR148 SMPD4 ARHGEF4 NOC2LP1 RAB6C

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding