Hs02004824_cn

• Gene Symbol: EXOSC7
• Assay Reference Genome Location: Chr.3:44989634 on build GRCh38
• Cytoband: 3p21.31

Target Gene Details

• Entrez Gene ID: 23016
• Gene Name: exosome component 7
• Gene Aliases: EAP1, RRP42, Rrp42p, hRrp42p, p8
• Location: Chr.3:44975291-45012668 on Build GRCh38
• Assay Gene Location: Overlaps Exon 3 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOSC7	NM_015004.3			NP_055819.2
	NR_023353.1
	XM_017005930.1			XP_016861419.1
	AK130053.1
	AK295779.1
	AK315741.1
	BC012831.2			AAH12831.1
	BU153856.1
	D29958.1			BAA06226.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834676	Chr.3:44928707 - 45149356 on Build GRCh38	Gain+Loss	CLEC3B ZDHHC3 CDCP1 EXOSC7

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, exoribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
RNA catabolic process
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U1 snRNA 3'-end processing
U4 snRNA 3'-end processing
U5 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
nuclear mRNA surveillance
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear polyadenylation-dependent mRNA catabolic process

Function(s)

3'-5'-exoribonuclease activity
RNA binding
exoribonuclease activity
protein binding
AU-rich element binding