Hs02060108_cn

• Gene Symbol: TDO2
• Assay Reference Genome Location: Chr.4:155911525 on build GRCh38
• Cytoband: 4q32.1

Target Gene Details

• Entrez Gene ID: 6999
• Gene Name: tryptophan 2,3-dioxygenase
• Gene Aliases: TDO, TO, TPH2, TRPO
• Location: Chr.4:155903693-155920406 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TDO2	NM_005651.3			NP_005642.1
	AK289418.1
	AK307741.1
	BC005355.1			AAH05355.1
	BX647341.1
	U32989.1			AAB08514.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3575777	Chr.4:155855410 - 156699594 on Build GRCh38	Gain	ASIC5 TDO2 CTSO
nsv830121	Chr.4:155850003 - 156002314 on Build GRCh38	Gain	ASIC5 TDO2 CTSO
nsv1029122	Chr.4:155773161 - 156031641 on Build GRCh38	Gain	ASIC5 GUCY1B3 TDO2 CTSO

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

tryptophan catabolic process
tryptophan catabolic process to kynurenine
tryptophan catabolic process to acetyl-CoA
oxidation-reduction process

Function(s)

tryptophan 2,3-dioxygenase activity
protein binding
amino acid binding
oxygen binding
heme binding
metal ion binding