Hs02082983_cn

• Gene Symbol: DLEU2
• Assay Reference Genome Location: Chr.13:49997128 on build GRCh38
• Cytoband: 13q14.2

Target Gene Details

• Entrez Gene ID: 8847
• Gene Name: deleted in lymphocytic leukemia 2 (non-protein coding)
• Gene Aliases: 1B4, BCMSUN, DLB2, LEU2, LINC00022, MIR15AHG, NCRNA00022, RFP2OS, TRIM13OS
• Location: Chr.13:49982552-50125541 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DLEU2	NR_002612.1
	AF529010.1
	AY455757.1

Target Gene Details

• Entrez Gene ID: 10206
• Gene Name: tripartite motif containing 13
• Gene Aliases: CAR, DLEU5, LEU5, RFP2, RNF77
• Location: Chr.13:49997007-50018467 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRIM13	NM_001007278.2	1	122	NP_001007279.1
	NM_005798.4			NP_005789.2
	NM_052811.3	1	122	NP_434698.1
	NM_213590.2	1	122	NP_998755.1
	AF220127.1			AAG53500.1
	AF241850.1			AAF91315.1
	AK314496.1	1	81
	AL360196.1
	AY191002.1	1	70	AAO38979.1
	AY455758.1	1	97	AAR31110.1
	AY764035.1	1	92	AAV51406.1
	BC003579.1	1	83	AAH03579.1
	BC063407.1	1	64	AAH63407.1
	BI668033.1	1	127

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv561618	Chr.13:49907577 - 51521449 on Build GRCh38	Loss	DLEU1 INTS6-AS1 MIR3613 TRIM13 GUCY1B2 KCNRG DLEU7 MIR5693 INTS6 MIR15A DLEU1-AS1 SERPINE3 DLEU2 ST13P4 MIR16-1 RNASEH2B FAM124A DLEU7-AS1 SPRYD7 LINC00371 RNASEH2B-AS1
nsv1035151	Chr.13:49939399 - 50593714 on Build GRCh38	Loss	DLEU1 DLEU2 ST13P4 MIR16-1 MIR3613 TRIM13 KCNRG MIR15A DLEU1-AS1

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

signal transduction
anatomical structure morphogenesis
response to gamma radiation
positive regulation of cell death
positive regulation of macroautophagy
ER-associated ubiquitin-dependent protein catabolic process
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
innate immune response
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
negative regulation of viral release from host cell

Function(s)

ubiquitin-protein transferase activity
signal transducer activity
protein binding
zinc ion binding
ligase activity