Hs02108256_cn

• Gene Symbol: ALDH1A2
• Assay Reference Genome Location: Chr.15:57962131 on build GRCh38
• Cytoband: 15q21.3

Target Gene Details

• Entrez Gene ID: 8854
• Gene Name: aldehyde dehydrogenase 1 family member A2
• Gene Aliases: RALDH(II), RALDH2, RALDH2-T
• Location: Chr.15:57953424-58065923 on Build GRCh38
• Assay Gene Location: Overlaps Intron 10 - Exon 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ALDH1A2	NM_001206897.1			NP_001193826.1
	NM_003888.3			NP_003879.2
	NM_170696.2			NP_733797.1
	NM_170697.2			NP_733798.1
	AB015226.1			BAA34785.1
	AB015227.1			BAA34786.1
	AB015228.1			BAA34787.1
	AK128709.1
	AK294981.1
	AK303057.1
	AL110299.1			CAB53740.2
	BC030589.2			AAH30589.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv569593	Chr.15:57909500 - 58016452 on Build GRCh38	Loss	ALDH1A2
nsv833023	Chr.15:57869641 - 58047976 on Build GRCh38	Gain	ALDH1A2

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

dehydrogenase, oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

blood vessel development
kidney development
liver development
regulation of endothelial cell proliferation
retinoic acid biosynthetic process
heart morphogenesis
vitamin A metabolic process
midgut development
positive regulation of cell proliferation
negative regulation of cell proliferation
determination of bilateral symmetry
anterior/posterior pattern specification
proximal/distal pattern formation
positive regulation of gene expression
neural crest cell development
morphogenesis of embryonic epithelium
neural tube development
pituitary gland development
neuron differentiation
lung development
hindbrain development
pancreas development
embryonic camera-type eye development
response to estradiol
response to vitamin A
response to cytokine
embryonic forelimb morphogenesis
ureter maturation
retinol metabolic process
retinoic acid metabolic process
retinal metabolic process
9-cis-retinoic acid biosynthetic process
positive regulation of apoptotic process
retinoic acid receptor signaling pathway
embryonic digestive tract development
cardiac muscle tissue development
oxidation-reduction process
face development
cellular response to retinoic acid

Function(s)

retinal dehydrogenase activity
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
retinal binding