Hs02154889_cn

• Gene Symbol: SERPINB5
• Assay Reference Genome Location: Chr.18:63477038 on build GRCh38
• Cytoband: 18q21.33

Target Gene Details

• Entrez Gene ID: 5268
• Gene Name: serpin family B member 5
• Gene Aliases: PI5, maspin
• Location: Chr.18:63476911-63505085 on Build GRCh38
• Assay Gene Location: Overlaps Exon 1 - Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINB5	NM_002639.4			NP_002630.2
	AK301667.1
	AK312765.1
	AL602439.1
	BC020713.1			AAH20713.1
	U04313.1			AAA18957.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1066552	Chr.18:63147299 - 64608176 on Build GRCh38	Gain	LINC00305 SERPINB5 VPS4B SERPINB10 KDSR SERPINB11 SERPINB3 SERPINB12 BCL2 SERPINB8 LOC284294 LINC01538 SERPINB7 SERPINB4 SERPINB2 HMSD SERPINB13
nsv131597	Chr.18:63473298 - 63482700 on Build GRCh38	Deletion	SERPINB5

More Information

Additional Information:

For this assay, SNP(s) [rs75113857] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

morphogenesis of an epithelium
movement of cell or subcellular component
negative regulation of endopeptidase activity
extracellular matrix organization
regulation of epithelial cell proliferation
prostate gland morphogenesis

Function(s)

serine-type endopeptidase inhibitor activity
protein binding