Hs02161541_cn

• Gene Symbol: NECAB3
• Assay Reference Genome Location: Chr.20:33658780 on build GRCh38
• Cytoband: 20q11.22

Target Gene Details

• Entrez Gene ID: 63941
• Gene Name: N-terminal EF-hand calcium binding protein 3
• Gene Aliases: APBA2BP, EFCBP3, NIP1, STIP3, SYTIP2, XB51, dJ63M2.4, dJ63M2.5
• Location: Chr.20:33657087-33674458 on Build GRCh38
• Assay Gene Location: Overlaps Intron 12 - Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NECAB3	NM_031231.3			NP_112508.3
	NM_031232.3			NP_112509.3
	XM_005260510.1			XP_005260567.1
	XM_011528991.1			XP_011527293.1
	XM_017028015.1			XP_016883504.1
	XM_017028016.1			XP_016883505.1
	AB039947.1			BAB16413.1
	AF193759.1			AAG28415.1
	AF409141.1			AAL01118.1
	AK023706.1			BAB14649.1
	AK124388.1
	AK291895.1
	BC047673.1			AAH47673.1
	BQ212085.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv585927	Chr.20:33656331 - 33663590 on Build GRCh38	Loss	C20orf144 NECAB3
nsv954024	Chr.20:33638795 - 33698694 on Build GRCh38	Deletion	CBFA2T2 ACTL10 C20orf144 E2F1 NECAB3
nsv1065189	Chr.20:33597378 - 33807579 on Build GRCh38	Loss	ZNF341-AS1 CBFA2T2 ACTL10 C20orf144 ZNF341 E2F1 NECAB3 PXMP4
nsv833961	Chr.20:33605380 - 33836992 on Build GRCh38	Loss	ZNF341-AS1 CBFA2T2 ACTL10 CHMP4B C20orf144 ZNF341 E2F1 NECAB3 PXMP4
dgv7560n54	Chr.20:33657740 - 33667228 on Build GRCh38	Loss	ACTL10 C20orf144 NECAB3
nsv833960	Chr.20:33569059 - 33688060 on Build GRCh38	Loss	CBFA2T2 ACTL10 C20orf144 E2F1 NECAB3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein secretion
protein metabolic process
regulation of amyloid precursor protein biosynthetic process

Function(s)

calcium ion binding
protein binding