Hs02164729_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76329546 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3	2	992	NP_036611.2
	AB024334.1	2	944	BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1	2	956
	AK293505.1	3	836
	AK295029.1	3	871
	BC020963.2	2	966	AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	FDPSP2 POMZP3 SRRM3 DTX2 DTX2P1-UPK3BP1-PMS2P11 HSPB1 SSC4D LOC105375355 LOC100133091 SPDYE16 ZP3 YWHAG
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	PMS2P9 DTX2 SSC4D CCDC146 LOC105375355 SPDYE17 SPDYE18 LOC100133091 SPDYE16 ZP3 YWHAG FDPSP2 POMZP3 DTX2P1-UPK3BP1-PMS2P11 FGL2
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	SPDYE5 DTX2 SSC4D LOC105375355 LOC441259 MIR4651 SNORA14A SPDYE16 LOC107986711 ZP3 YWHAG TRIM73 POMZP3 SRRM3 POR LOC541473 HSPB1 TMEM120A POM121C GTF2IRD2B NCF1C GTF2IP1 GTF2IP7 PMS2P2 CCL26 CCL24 RHBDD2 PMS2P10 STYXL1 PMS2P3 HIP1 LOC100133091 NSUN5P1 FDPSP2 STAG3L1 MDH2
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SPDYE5 DTX2 SSC4D LOC105375355 MIR4651 SNORA14A SPDYE16 LOC107986711 ZP3 YWHAG POMZP3 SRRM3 POR HSPB1 TMEM120A POM121C GTF2IP7 CCL26 CCL24 RHBDD2 STYXL1 PMS2P3 HIP1 LOC100133091 FDPSP2 MDH2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding