Hs02169779_cn

• Gene Symbol: SIPA1
• Assay Reference Genome Location: Chr.11:65647477 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 6494
• Gene Name: signal-induced proliferation-associated 1
• Gene Aliases: SPA1
• Location: Chr.11:65638107-65650930 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SIPA1	NM_006747.3	9	2292	NP_006738.3
	NM_153253.29	9	2421	NP_694985.29
	XM_005274189.2	9	2366	XP_005274246.1
	XM_011545214.1	9	2332	XP_011543516.1
	AB005666.1	9	2421	BAA22197.1
	AF029789.1	9	2274	AAC32547.1
	AK303551.1	10	2060
	AK308234.1	9	2263
	AK310068.1
	BC010492.1	9	2243	AAH10492.1
	BC110353.1	9	2261	AAI10354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv1969n54	Chr.11:65568234 - 65663889 on Build GRCh38	Loss	MIR4489 SIPA1 MAP3K11 FAM89B EHBP1L1 SSSCA1-AS1 KCNK7 MIR4690 SSSCA1 PCNX3 RELA
nsv951018	Chr.11:65525430 - 65662029 on Build GRCh38	Deletion	MIR4489 MAP3K11 EHBP1L1 LTBP3 SSSCA1-AS1 SSSCA1 RELA SIPA1 SCYL1 FAM89B KCNK7 MIR4690 PCNX3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

cytoskeleton organization
negative regulation of cell adhesion
signal transduction
cell proliferation
negative regulation of cell growth
intracellular signal transduction
cellular response to water deprivation
positive regulation of GTPase activity
negative regulation of cell cycle
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
protein C-terminus binding