Hs02188112_cn

• Gene Symbol: ITGB5
• Assay Reference Genome Location: Chr.3:124773781 on build GRCh38
• Cytoband: 3q21.2

Target Gene Details

• Entrez Gene ID: 3693
• Gene Name: integrin subunit beta 5
• Gene Aliases: -
• Location: Chr.3:124761948-124901411 on Build GRCh38
• Assay Gene Location: Within Exon 14

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ITGB5	NM_002213.4	11	2130	NP_002204.2
	XM_005247436.2	10	2273	XP_005247493.1
	XM_006713630.2	10	2228	XP_006713693.1
	XM_017006351.1	11	1901	XP_016861840.1
	XM_017006352.1	11	1840	XP_016861841.1
	XM_017006353.1	11	1872	XP_016861842.1
	XM_017006354.1	8	2015	XP_016861843.1
	XM_017006355.1	10	1750	XP_016861844.1
	AK130168.1	4	755
	AK309551.1	3	616
	AK315429.1	11	1866
	BC006541.2	11	2122	AAH06541.1
	J05633.1	11	1871	AAA59183.1
	M35011.1	11	1854	AAA52707.1
	X53002.1	11	2161	CAA37188.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1012242	Chr.3:124722848 - 124797029 on Build GRCh38	Gain	UMPS ITGB5 MIR544B KALRN
nsv1001677	Chr.3:124015843 - 125108694 on Build GRCh38	Loss	UMPS HEG1 ITGB5 MIR544B MIR6083 SLC12A8 KALRN MUC13 MIR5002
nsv1160974	Chr.3:124577493 - 125300995 on Build GRCh38	Duplication	UMPS HEG1 ITGB5 MIR544B SLC12A8 KALRN MIR5092 MUC13 ZNF148
nsv3981	Chr.3:124757649 - 124788489 on Build GRCh38	Insertion	ITGB5

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
muscle contraction
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
extracellular matrix organization
endodermal cell differentiation
stress fiber assembly
viral entry into host cell
epithelial cell-cell adhesion

Function(s)

virus receptor activity
protein binding