Hs02203611_cn

• Gene Symbol: CDK12
• Assay Reference Genome Location: Chr.17:39462334 on build GRCh38
• Cytoband: 17q12

Target Gene Details

• Entrez Gene ID: 51755
• Gene Name: cyclin dependent kinase 12
• Gene Aliases: CRK7, CRKR, CRKRS
• Location: Chr.17:39461486-39567560 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDK12	NM_015083.2	1	824	NP_055898.1
	NM_016507.3	1	824	NP_057591.2
	XM_005257456.3	1	849	XP_005257513.1
	XM_005257458.4	1	849	XP_005257515.1
	XM_011524892.2	1	849	XP_011523194.1
	XM_011524893.2	1	849	XP_011523195.1
	XM_011524894.2	1	849	XP_011523196.1
	XM_011524895.2	1	849	XP_011523197.1
	XM_011524896.2	1	849	XP_011523198.1
	XM_011524897.2	1	849	XP_011523199.1
	XM_011524898.2	1	849	XP_011523200.1
	XM_011524899.2	1	849	XP_011523201.1
	XM_011524900.2	1	849	XP_011523202.1
	XM_011524901.2	1	849	XP_011523203.1
	XM_011524902.2	1	849	XP_011523204.1
	XM_011524903.2	1	849	XP_011523205.1
	XM_011524905.2	1	849	XP_011523207.1
	XM_011524906.2	1	849	XP_011523208.1
	XM_011524907.2	1	849	XP_011523209.1
	XM_017024744.1	1	849	XP_016880233.1
	XM_017024745.1	1	849	XP_016880234.1
	XM_017024746.1	1	849	XP_016880235.1
	XM_017024747.1	1	849	XP_016880236.1
	XM_017024748.1	1	849	XP_016880237.1
	XM_017024749.1	1	849	XP_016880238.1
	XM_017024750.1	1	849	XP_016880239.1
	XM_017024751.1	1	849	XP_016880240.1
	XM_017024752.1	1	849	XP_016880241.1
	XM_017024753.1	1	849	XP_016880242.1
	AB020711.2	1	574
	AF227198.1	1	296	AAF36401.1
	AK302645.1	1	824
	BC140854.1	1	283
	BC150265.1	1	580

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv827985	Chr.17:39461255 - 39463008 on Build GRCh38	Loss	CDK12
nsv1063848	Chr.17:39419369 - 39551339 on Build GRCh38	Gain	CDK12 MED1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

mRNA processing
RNA splicing
regulation of MAP kinase activity
regulation of RNA splicing
protein autophosphorylation
regulation of cell cycle
phosphorylation of RNA polymerase II C-terminal domain

Function(s)

protein kinase activity
cyclin-dependent protein serine/threonine kinase activity
protein binding
ATP binding
RNA polymerase II carboxy-terminal domain kinase activity
cyclin binding