Hs02208630_cn

• Gene Symbol: NLRP4
• Assay Reference Genome Location: Chr.19:55852191 on build GRCh38
• Cytoband: 19q13.43

Target Gene Details

• Entrez Gene ID: 147945
• Gene Name: NLR family pyrin domain containing 4
• Gene Aliases: CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2
• Location: Chr.19:55836578-55881855 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NLRP4	NM_134444.4	2	533	NP_604393.2
	XM_017026344.1	1	176	XP_016881833.1
	XM_017026345.1	1	176	XP_016881834.1
	AF442488.1	1	168	AAL35293.1
	AF479747.1	1	180	AAL87104.1
	AF482706.1	1	178	AAL88672.1
	AK315003.1	2	533
	AY072792.1	1	171	AAL68396.1
	BC050326.1	2	207	AAH50326.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644849	Chr.19:55836319 - 55989037 on Build GRCh38	Gain	NLRP13 NLRP4 NLRP11 NLRP8
esv3644851	Chr.19:55843395 - 56076000 on Build GRCh38	Gain	NLRP13 LOC101928886 NLRP4 NLRP5 NLRP8
nsv580346	Chr.19:55735154 - 55857948 on Build GRCh38	Gain	RFPL4AL1 NLRP9 NLRP4 NLRP11 RFPL4A
nsv820912	Chr.19:55849640 - 55852405 on Build GRCh38	Deletion	NLRP4
dgv6582n54	Chr.19:55807428 - 56027874 on Build GRCh38	Gain	NLRP13 NLRP4 NLRP11 NLRP5 NLRP8
nsv1064105	Chr.19:55808050 - 55939166 on Build GRCh38	Gain	NLRP13 NLRP4 NLRP11
esv3893253	Chr.19:55805430 - 55857497 on Build GRCh38	Loss	NLRP4 NLRP11
esv3644852	Chr.19:55848269 - 55916219 on Build GRCh38	Gain	NLRP13 NLRP4
nsv1057383	Chr.19:55699665 - 55944662 on Build GRCh38	Gain	NLRP13 RFPL4AL1 NLRP9 NLRP4 NLRP11 RFPL4A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

inflammatory response
regulation of type I interferon production

Function(s)

ATP binding