Hs02256422_cn

• Gene Symbol: TMPRSS2
• Assay Reference Genome Location: Chr.21:41465901 on build GRCh38
• Cytoband: 21q22.3

Target Gene Details

• Entrez Gene ID: 7113
• Gene Name: transmembrane protease, serine 2
• Gene Aliases: PP9284, PRSS10
• Location: Chr.21:41464551-41508158 on Build GRCh38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TMPRSS2	NM_001135099.1	14	1892	NP_001128571.1
	NM_005656.3	14	1854	NP_005647.3
	XM_005261043.2	13	1734	XP_005261100.1
	XM_011529733.1	12	1553	XP_011528035.1
	AF318374.1	1	947	AAL55881.1
	AF329454.1	14	1847	AAK53559.1
	AK123948.1	1	1188
	AK222784.1	13	1765	BAD96504.1
	AK296860.1	14	1892
	BC051839.1	14	1825	AAH51839.1
	U75329.1	13	1776	AAC51784.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv587496	Chr.21:41458763 - 41494180 on Build GRCh38	Loss	TMPRSS2 MX1
nsv834102	Chr.21:41286267 - 41494006 on Build GRCh38	Loss	TMPRSS2 MX2 FAM3B MX1
esv3647063	Chr.21:41455441 - 41527402 on Build GRCh38	Gain	TMPRSS2 MX1
esv3647064	Chr.21:41456009 - 41569886 on Build GRCh38	Gain	TMPRSS2 MX1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Process(es)

proteolysis
receptor-mediated endocytosis
protein autoprocessing
positive regulation of viral entry into host cell

Function(s)

serine-type endopeptidase activity
scavenger receptor activity
protein binding
serine-type peptidase activity