Hs02256460_cn

• Gene Symbol: DGKE
• Assay Reference Genome Location: Chr.17:56835062 on build GRCh38
• Cytoband: 17q22

Target Gene Details

• Entrez Gene ID: 8526
• Gene Name: diacylglycerol kinase epsilon
• Gene Aliases: AHUS7, DAGK5, DAGK6, DGK, NPHS7
• Location: Chr.17:56834099-56869565 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DGKE	NM_003647.2	2	447	NP_003638.1
	XM_011525394.2	2	425	XP_011523696.1
	XM_011525395.2	2	432	XP_011523697.1
	XM_011525396.2	2	434	XP_011523698.1
	XM_017025243.1	2	442	XP_016880732.1
	XM_017025244.1	2	428	XP_016880733.1
	XM_017025245.1	2	431	XP_016880734.1
	AB209365.1	1	97	BAD92602.1
	AK293039.1	2	394
	AK310668.1	2	415
	AL555194.3	2	447
	BC022297.1	2	439	AAH22297.1
	BC130629.1	1	291
	BC130631.1	1	291
	DB221284.1	1	108
	U49379.1	2	354	AAC50497.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv32884	Chr.17:56683534 - 57002132 on Build GRCh38	Loss	MIR3614 DGKE SCPEP1 MTVR2 TRIM25 C17orf67 COIL
nsv833495	Chr.17:56675225 - 56862382 on Build GRCh38	Loss	DGKE C17orf67

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

protein kinase C-activating G-protein coupled receptor signaling pathway
phospholipid biosynthetic process
phosphorylation
platelet activation
intracellular signal transduction

Function(s)

diacylglycerol kinase activity
ATP binding
metal ion binding