Hs02264981_cn

• Gene Symbol: POLM
• Assay Reference Genome Location: Chr.7:44073870 on build GRCh38
• Cytoband: 7p13

Target Gene Details

• Entrez Gene ID: 27434
• Gene Name: DNA polymerase mu
• Gene Aliases: Pol Mu, Tdt-N
• Location: Chr.7:44072062-44082540 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLM	NM_001284330.1	7	1089	NP_001271259.1
	NM_001284331.1	8	1218	NP_001271260.1
	NM_013284.3	9	1329	NP_037416.1
	NR_104299.1	9	1300
	XM_005249711.2	6	880	XP_005249768.1
	XM_006715692.2	9	1300	XP_006715755.1
	XM_006715696.2	7	1030	XP_006715759.1
	XM_006715698.3	4	1184	XP_006715761.1
	XM_011515275.1	9	1315	XP_011513577.1
	XM_011515278.1	8	1165	XP_011513580.1
	XM_011515279.1	9	1315	XP_011513581.1
	XM_011515282.2	4	1181	XP_011513584.1
	XM_011515285.1	5	567	XP_011513587.1
	XM_017011998.1	8	1129	XP_016867487.1
	XM_017011999.1	7	1075	XP_016867488.1
	XM_017012000.1	8	1165	XP_016867489.1
	XM_017012001.1	7	1075	XP_016867490.1
	XM_017012002.1	8	1145	XP_016867491.1
	XM_017012003.1	6	893	XP_016867492.1
	AF176097.1	9	1269	AAF26284.1
	AJ131891.2	9	1272	CAB65075.2
	AK023002.1	9	1275	BAB14353.1
	AK092903.1	5	1052
	AK307634.1
	BC026306.1	8	1872	AAH26306.1
	BC049202.1	7	1034
	BC062590.1	8	1142	AAH62590.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv830983	Chr.7:44068842 - 44201624 on Build GRCh38	Loss	MYL7 GCK YKT6 MIR6838 AEBP1 POLD2 POLM MIR4649
nsv8082	Chr.7:43956156 - 44207229 on Build GRCh38	Gain	GCK YKT6 AEBP1 SPDYE1 LINC00957 POLM MIR6837 MIR4649 DBNL MYL7 PGAM2 POLR2J4 MIR6838 POLD2 RASA4CP
nsv428165	Chr.7:43855828 - 44172960 on Build GRCh38	Gain	GCK UBE2D4 AEBP1 SPDYE1 LINC00957 POLM MIR6837 MIR4649 DBNL MRPS24 MYL7 LOC107986791 PGAM2 URGCP URGCP-MRPS24 POLR2J4 MIR6838 POLD2 RASA4CP
nsv470210	Chr.7:44045936 - 44139229 on Build GRCh38	Loss	MYL7 PGAM2 MIR6838 AEBP1 POLD2 POLM MIR6837 MIR4649 DBNL
nsv830980	Chr.7:43865998 - 44078539 on Build GRCh38	Loss	UBE2D4 SPDYE1 LINC00957 POLM MIR6837 DBNL MRPS24 LOC107986791 PGAM2 URGCP URGCP-MRPS24 POLR2J4 MIR6838 RASA4CP

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed DNA polymerase

Gene Ontology Categories:

Process(es)

double-strand break repair via nonhomologous end joining
DNA recombination
somatic hypermutation of immunoglobulin genes
B cell differentiation
DNA biosynthetic process

Function(s)

DNA binding
DNA-directed DNA polymerase activity
protein binding
metal ion binding